Selective serotonin reuptake inhibitor-induced rhabdomyolysis associated with irinotecan

被引：23
作者：
Richards, S
Umbreit, JN
Fanucchi, MP
Giblin, J
Khuri, F
机构：
[1] Emory Univ, Sch Med, Winship Canc Inst, Atlanta, GA 30322 USA
[2] Emory Univ, Sch Med, Dept Med, Atlanta, GA 30322 USA
来源：
SOUTHERN MEDICAL JOURNAL | 2003年 / 96卷 / 10期
关键词：
citalopram; irinotecan; rhabdomyolysis; selective serotonin reuptake inhibitors;
D O I：
10.1097/01.SMJ.0000084311.35864.D6
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 74-year-old man was admitted with rhabdomyolysis after undergoing initial treatment for gastrointestinal cancer with irinotecan. The syndrome partially resolved after the discontinuation of all of his usual medications, including his chronic selective serotonin reuptake inhibitor (SSRI). The rhabdomyolysis was exacerbated upon reinitiation of the SSRI and disappeared when the SSRI was discontinued. The combination of irinotecan and SSRI resulted in potentially lethal rhabdomyolysis.
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收藏
页码：1031 / 1033
页数：3
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