FDG PET/MR for the Assessment of Lymph Node Involvement in Lymphoma: Initial Results and Role of Diffusion-Weighted MR

被引：18

作者：

Platzek, Ivan ^{[1
]}

Beuthien-Baumann, Bettina ^{[2
]}

Ordemann, Rainer ^{[3
]}

Maus, Jens ^{[4
]}

Schramm, Georg ^{[4
]}

Kitzler, Hagen H. ^{[5
]}

Laniado, Michael ^{[1
]}

Kotzerke, Joerg ^{[2
]}

van den Hoff, Joerg ^{[4
]}

机构：

[1] Dresden Univ Hosp, Dept Radiol, D-01307 Dresden, Germany

[2] Dresden Univ Hosp, Dept Nucl Med, D-01307 Dresden, Germany

[3] Dresden Univ Hosp, Dept Internal Med, D-01307 Dresden, Germany

[4] Helmholtz Zentrum Dresden Rossendorf, Inst Radiopharmaceut Canc Res, Dresden, Germany

[5] Dresden Univ Hosp, Dept Neuroradiol, D-01307 Dresden, Germany

来源：

ACADEMIC RADIOLOGY | 2014年 / 21卷 / 10期

关键词：

Lymphoma; PET/MR; staging; sensitivity; specificity; POSITRON-EMISSION-TOMOGRAPHY; PERFORMANCE; CONSENSUS;

D O I：

10.1016/j.acra.2014.05.019

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Rationale and Objectives: The purpose of this study was to evaluate the sensitivity and specificity of positron emission tomography/magnetic resonance imaging (PET/MR) with 18F-fluorodeoxyglucose (FDG) for nodal involvement in malignant lymphoma. Materials and Methods: Twenty-seven patients with malignant lymphoma (16 men and 11 women; mean age, 45 years) were included in this retrospective study. The patients underwent FDG PET/MR after intravenous injection of FDG (176-357 MBq FDG, 282 MBq on average). Follow-up imaging and histology served as the standard of reference. Results: One-hundred and twenty-seven (18.1%) of 702 lymph node stations were rated as having lymphoma-involvement based on the standard of reference. One-hundred and twenty-four (17.7%) of 702 lymph node stations were rated as positive by FDG PET/MR. The sensitivity and specificity of FDG PET/MR for lymph node station involvement were 93.8% and 99.4%. Conclusions: FDG PET/MR is feasible for lymphoma staging and has a high-sensitivity and specificity for nodal involvement in lymphoma. Comparison with PET/CT is necessary to determine whether FDG PET/MR can replace PET/CT for lymphoma staging.

引用

页码：1314 / 1319

页数：6

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