FDG PET/MR for the Assessment of Lymph Node Involvement in Lymphoma: Initial Results and Role of Diffusion-Weighted MR

被引:18
作者
Platzek, Ivan [1 ]
Beuthien-Baumann, Bettina [2 ]
Ordemann, Rainer [3 ]
Maus, Jens [4 ]
Schramm, Georg [4 ]
Kitzler, Hagen H. [5 ]
Laniado, Michael [1 ]
Kotzerke, Joerg [2 ]
van den Hoff, Joerg [4 ]
机构
[1] Dresden Univ Hosp, Dept Radiol, D-01307 Dresden, Germany
[2] Dresden Univ Hosp, Dept Nucl Med, D-01307 Dresden, Germany
[3] Dresden Univ Hosp, Dept Internal Med, D-01307 Dresden, Germany
[4] Helmholtz Zentrum Dresden Rossendorf, Inst Radiopharmaceut Canc Res, Dresden, Germany
[5] Dresden Univ Hosp, Dept Neuroradiol, D-01307 Dresden, Germany
关键词
Lymphoma; PET/MR; staging; sensitivity; specificity; POSITRON-EMISSION-TOMOGRAPHY; PERFORMANCE; CONSENSUS;
D O I
10.1016/j.acra.2014.05.019
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Rationale and Objectives: The purpose of this study was to evaluate the sensitivity and specificity of positron emission tomography/magnetic resonance imaging (PET/MR) with 18F-fluorodeoxyglucose (FDG) for nodal involvement in malignant lymphoma. Materials and Methods: Twenty-seven patients with malignant lymphoma (16 men and 11 women; mean age, 45 years) were included in this retrospective study. The patients underwent FDG PET/MR after intravenous injection of FDG (176-357 MBq FDG, 282 MBq on average). Follow-up imaging and histology served as the standard of reference. Results: One-hundred and twenty-seven (18.1%) of 702 lymph node stations were rated as having lymphoma-involvement based on the standard of reference. One-hundred and twenty-four (17.7%) of 702 lymph node stations were rated as positive by FDG PET/MR. The sensitivity and specificity of FDG PET/MR for lymph node station involvement were 93.8% and 99.4%. Conclusions: FDG PET/MR is feasible for lymphoma staging and has a high-sensitivity and specificity for nodal involvement in lymphoma. Comparison with PET/CT is necessary to determine whether FDG PET/MR can replace PET/CT for lymphoma staging.
引用
收藏
页码:1314 / 1319
页数:6
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