Comparison of weight bearing functional exercise and non-weight bearing quadriceps strengthening exercise on pain and function for people with knee osteoarthritis and obesity: protocol for the TARGET randomised controlled trial

被引：24

作者：

Bennell, Kim L. ^{[1
]}

Nelligan, Rachel K. ^{[1
]}

Kimp, Alexander J. ^{[1
]}

Wrigley, Tim V. ^{[1
]}

Metcalf, Ben ^{[1
]}

Kasza, Jessica ^{[2
]}

Hodges, Paul W. ^{[3
]}

Hinman, Rana S. ^{[1
]}

机构：

[1] Univ Melbourne, Ctr Hlth Exercise & Sports Med, Dept Physiotherapy, Sch Hlth Sci, Melbourne, Vic, Australia

[2] Monash Univ Melbourne, Sch Publ Hlth & Prevent Med, Melbourne, Vic, Australia

[3] Univ Queensland, Ctr Clin Res Excellence Spinal Pain Injury & Hlth, Sch Hlth & Rehabil Sci, Brisbane, Qld, Australia

来源：

BMC MUSCULOSKELETAL DISORDERS | 2019年 / 20卷 / 1期

基金：

英国医学研究理事会;

关键词：

Osteoarthritis; Knee; Physiotherapy; Exercise; Obesity; Clinical trial; RCT; PSYCHOMETRIC EVALUATION; RECOMMENDATIONS DESIGN; CLINICAL-TRIALS; GLOBAL BURDEN; SCALE; HIP; INTERVENTIONS; INSTRUMENT; PATIENT; ASSOCIATION;

D O I：

10.1186/s12891-019-2662-5

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

BackgroundClinical guidelines recommend exercise as a core treatment for individuals with knee osteoarthritis (OA). However, the best type of exercise for clinical benefits is not clear, particularly in different OA subgroups. Obesity is a common co-morbidity in people with knee OA. There is some evidence suggesting that non-weight bearing exercise may be more effective than weight bearing exercise in patients with medial knee OA and obesity.MethodsTo compare the efficacy of two different exercise programs (weight bearing functional exercise and non-weight bearing quadriceps strengthening) on pain and physical function for people 50years with painful medial knee OA and obesity (body mass index 30kg/m(2)) 128 people in Melbourne, Australia will be recruited for a two group parallel-design, assessor- and participant-blinded randomised controlled trial. Participants will be randomly allocated to undertake a program of either weight bearing functional exercise or non-weight bearing quadriceps strengthening exercise. Both groups will attend five individual sessions with a physiotherapist who will teach, monitor and progress the exercise program. Participants will be asked to perform the exercises at home four times per week for 12weeks. Outcomes will be measured at baseline and 12weeks. Primary outcomes are self-reported knee pain and physical function. Secondary outcomes include other measures of knee pain, physical function, quality-of-life, participant-perceived global change, physical performance, and lower limb muscle strength.DiscussionThis study will compare the efficacy of two different 12-week physiotherapist-prescribed, home-based exercise programs for people with medial knee OA and obesity. Findings will provide valuable information to help inform exercise prescription in this common OA patient subgroup.Trial registrationAustralian New Zealand Clinical Trials Registry reference: ACTRN12617001013358, 14/7/2017

引用

页数：10

共 51 条

[11] THE INCREASE OF PERCEIVED EXERTION, ACHES AND PAIN IN THE LEGS, HEART-RATE AND BLOOD LACTATE DURING EXERCISE ON A BICYCLE ERGOMETER [J].