Spectrophotometric determination of thyroxine sodium in drug formulations

被引：0

作者：

Qureshi, SZ

Helaleh, MI

Rahman, N

Jamhour, RMAQ

机构：

来源：

CHEMIA ANALITYCZNA | 1997年 / 42卷 / 01期

关键词：

thyroxine sodium; reaction with nitrous acid; spectrophotometry-VIS;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The spectrophotometric determination of thyroxine sodium is based on reaction of its amine group with nitrous acid (produced by reaction of mineral acid with sodium nitrite) in an ice cold bath (0-5 degrees C). It produces a stable yellow coloured compound under experimental conditions with lambda(max) 420 nm. Beer's law is obeyed in the concentration range 10-90 mu g ml(-1) with molar absorptivity 4.0x10(3) l mol(-1) cm(-1).

引用

页码：65 / 69

页数：5