Green Synthesis and Antibacterial Activity of HAp@Ag Nanocomposite Using Centella asiatica (L.) Urban Extract and Eggshell

被引:21
作者
Pham, Xuan Nui [1 ]
Nguyen, Hoa Thi [1 ]
Pham, Ngan Thi [1 ]
机构
[1] Hanoi Univ Min & Geol, Dept Chem Engn, 18 Vien St, Hanoi, Vietnam
关键词
SILVER NANOPARTICLES; COMPOSITE SCAFFOLDS; POMEGRANATE EXTRACT; AERIAL PARTS; HYDROXYAPATITE; POWDERS; FILMS;
D O I
10.1155/2020/8841221
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
In recent years, the green synthesis of nanoparticles via biological processes has attracted considerable attention. Herein, we introduce a facile and green approach for the synthesis of poriferous silver nanoparticles (Ag-NPs) decorated hydroxylapatite (HAp@Ag) nanoparticles with excellent antibacterial properties. All the nanocomposites were fully characterized in the solid state via various techniques such as X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), and energy-dispersive X-ray spectrometer (EDX), in which the synthesized Ag-NPs (24 nm in diameter) and their homogeneous incorporation on HAp have been studied by ultraviolet-visible (UV-vis) technique, transmission electron microscopy (TEM), and dynamic light scattering (DLS) analysis. The obtained results indicate that the structure and morphology of HAp have no significant changes after the incorporation of Ag-NPs on its surface. Moreover, an impressive antibacterial activity of HAp@Ag nanocomposite against Gram-positive bacteriumStaphylococcus aureusand Gram-negative bacteriaEscherichia coliandPseudomonas aeruginosahas been recorded by using the agar well diffusion method.As a result, the HAp@Ag nanocomposite promises to be a great biomedical material with high antibacterial properties.
引用
收藏
页数:12
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