Utility of Combining PET and MR Imaging of Carotid Plaque

被引：23

作者：

Vesey, Alex T. ^{[1
]}

Dweck, Marc R. ^{[1
,2
,3
]}

Fayad, Zahi A. ^{[2
,3
]}

机构：

[1] Univ Edinburgh, British Heart Fdn Ctr Cardiovasc Sci, Coll Med & Vet Med, Edinburgh EH16 4SB, Midlothian, Scotland

[2] Mt Sinai Sch Med, Translat & Mol Imaging Inst, Dept Radiol, Imaging Sci Labs, New York, NY 10029 USA

[3] Mt Sinai Sch Med, Translat & Mol Imaging Inst, Dept Med, Imaging Sci Labs, New York, NY 10029 USA

来源：

NEUROIMAGING CLINICS OF NORTH AMERICA | 2016年 / 26卷 / 01期

关键词：

PET; MR imaging; Carotid plaque imaging; POSITRON-EMISSION-TOMOGRAPHY; IN-VIVO; MACROPHAGE ACTIVITY; ATHEROSCLEROSIS; INFLAMMATION; BURDEN; NANOPARTICLES; HEMORRHAGE; ATHEROMA; HYPOXIA;

D O I：

10.1016/j.nic.2015.09.005

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

By harnessing the versatility and soft tissue imaging capabilities of MR imaging alongside the unmatched sensitivity and biomolecular flexibility of PET, the potential to provide detailed multiparametric plaque characterization in the carotid arteries is clear. The ability to acquire simultaneous, and dynamic multimodal data is perhaps PET/MR's greatest strength that will be of major interest to researchers investigating carotid and coronary atherosclerosis alike. This review summarizes the current status of dedicated hybrid PET/MR imaging, to crystallize the rationale for and advantages of this technique with respect to carotid atherosclerosis, and to discuss current limitations, challenges, and future directions.

引用

页码：55 / +

页数：15

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