Copper/amine-catalyzed formal regioselective [3+2] cycloaddition of an α,β-unsaturated O-acetyl oxime with enals

被引：43
作者：
Xie, Ying [1 ]
Li, Yulong [1 ]
Chen, Xun [2 ]
Liu, Yingle [1 ]
Zhang, Wei [1 ]
机构：
[1] Sichuan Univ Sci & Engn, Sch Chem & Environm Engn, Zigong 643000, Peoples R China
[2] Hainan Med Univ, Sch Pharm, Haikou 571199, Hainan, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2018年 / 5卷 / 10期
关键词：
C-H FUNCTIONALIZATION; ONE-POT SYNTHESIS; CONCISE SYNTHESES; PYRROLES; PYRIDINES; DERIVATIVES; KETOXIMES; INDOLES; ALKYNES; LAMELLARINS;
D O I：
10.1039/c8qo00204e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel copper/amine co-catalyzed formal regioselective [3 + 2] cycloaddition reaction of an O-acyl oxime with ,-unsaturated aldehydes is developed. This novel transformation provided an efficient protocol for the assembly of multifunctionalized pyrroles with good yields and diverse functional group tolerance.
引用
收藏
页码：1698 / 1701
页数：4
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