From PET/CT to PET/MRI: Advances in Instrumentation and Clinical Applications

被引：33
作者：
Hu, Zhenhua [1 ]
Yang, Weidong [2 ]
Liu, Haixiao [1 ]
Wang, Kun [1 ]
Bao, Chengpeng [1 ]
Song, Tianming [1 ]
Wang, Jing [2 ]
Tian, Jie [1 ]
机构：
[1] Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China
[2] Fourth Mil Med Univ, Xijing Hosp, Dept Nucl Med, Xian 710032, Peoples R China
来源：
MOLECULAR PHARMACEUTICS | 2014年 / 11卷 / 11期
基金：
中国国家自然科学基金;
关键词：
positron emission tomography/computed tomography (PET/CT); positron emission tomography/magnetic resonance imaging (PET/MRI); time-of-flight (TOF); silicon photomultiplier (SiPM); attenuation correction; oncology; neurologic disease; cardiology; CORONARY-ARTERY-DISEASE; POSITRON-EMISSION-TOMOGRAPHY; DIFFUSION-WEIGHTED MRI; ATTENUATION-CORRECTION; DIAGNOSTIC PERFORMANCE; MYOCARDIAL VIABILITY; LESION DETECTION; HYBRID PET/MRI; NECK-CANCER; RB-82; PET;
D O I：
10.1021/mp500321h
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Multimodality imaging of positron emission tomography/computed tomography (PET/CT) provides both metabolic information and the anatomic structure, which is significantly superior to either PET or CT alone and has greatly improved its clinical applications. Because of the higher soft-tissue contrast of magnetic resonance imaging (MRI) and no extra ionizing radiation, PET/MRI imaging is the hottest topic currently. PET/MRI is swiftly making its way into clinical practice. However, it has many technical difficulties to overcome, such as photomultiplier tubes, which cannot work properly in a magnetic field, and the inability to provide density information on the object for attenuation correction. This paper introduces the technique process of PET/MRI and summarizes its clinical applications, including imaging in oncology, neurology, and cardiology.
引用
收藏
页码：3798 / 3809
页数：12
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