Meningocele and ankyloblepharon following in utero exposure to olanzapine

被引：14
作者：
Arora, M. [1 ]
Praharaj, S. K. [1 ]
机构：
[1] Cent Inst Psychiat, Ranchi 834006, Jharkhand, India
来源：
EUROPEAN PSYCHIATRY | 2006年 / 21卷 / 05期
关键词：
olanzapine; ankyloblepharon; meningocele; teratogenicity;
D O I：
10.1016/j.eurpsy.2006.01.014
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Although atypical antipsychotics are widely used during pregnancy, their safety is not well established. This case highlights the possible teratogenic effect of olanzapine, in which the baby was born with meningocele and ankyloblepharon. It is suggested that olanzapine may interfere with embryonic development at different stages of pregnancy. (c) 2006 Elsevier SAS. All rights reserved.
引用
收藏
页码：345 / 346
页数：2
相关论文
共 12 条
  • [1] Adverse pregnancy outcome in schizophrenic women: occurrence and risk factors
    Bennedsen, BE
    [J]. SCHIZOPHRENIA RESEARCH, 1998, 33 (1-2) : 1 - 26
  • [2] CASIANO ME, 1987, PSYCHIAT CLIN N AM, V10, P35
  • [3] Dickson RA, 1998, CAN J PSYCHIAT, V43, P196
  • [4] Olanzapine-exposed pregnancies and lactation: Early experience
    Goldstein, DJ
    Corbin, LA
    Fung, MC
    [J]. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2000, 20 (04) : 399 - 403
  • [5] SYNDROME OF ANKYLOBLEPHARON, ECTODERMAL DEFECTS AND CLEFT-LIP AND PALATE - AUTOSOMAL DOMINANT CONDITION
    HAY, RJ
    WELLS, RS
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 1976, 94 (03) : 277 - 289
  • [6] Kirchheiner J, 2000, PHARMACOPSYCHIATRY, V33, P78
  • [7] Olanzapine and pregnancy
    Lim, LM
    [J]. AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 2001, 35 (06) : 856 - 857
  • [8] Antipsychotics during pregnancy
    Littrell, KH
    Johnson, CG
    Peabody, CD
    Hilligoss, N
    [J]. AMERICAN JOURNAL OF PSYCHIATRY, 2000, 157 (08) : 1342 - 1342
  • [9] Pregnancy outcome of women using atypical antipsychotic drugs: A prospective comparative study
    McKenna, K
    Koren, G
    Tetelbaum, M
    Wilton, L
    Shakir, S
    Diav-Citrin, O
    Levinson, A
    Zipursky, RB
    Einarson, A
    [J]. JOURNAL OF CLINICAL PSYCHIATRY, 2005, 66 (04) : 444 - 449
  • [10] Olanzapine and pregnancy
    Mendhekar, DN
    War, L
    Sharma, JB
    Jiloha, RC
    [J]. PHARMACOPSYCHIATRY, 2002, 35 (03) : 122 - 123
12