Adenovirus infections in transplant recipients

被引:239
作者
Ison, MG [1 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Div Infect Dis, Transplant Infect Dis Serv, Chicago, IL 60611 USA
关键词
D O I
10.1086/505498
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Adenoviruses are increasingly recognized as contributors to morbidity and mortality among stem cell and solid-organ transplant recipients. Clinical presentations range from asymptomatic viremia to respiratory and gastrointestinal disease, hemorrhagic cystitis, and severe disseminated illness. The limited clinical data available support the use of cidofovir for many of these illnesses. Prospective studies are needed to better understand the pathogenesis of and therapeutic options for adenoviral infections in this patient population.
引用
收藏
页码:331 / 339
页数:9
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