IFN-γ-induced nitric oxide leads to inhibition of Th17 differentiation via induction of iNOS and nitration of ROR-γ T

被引：0
|
作者：
Robinson-Joern, Rachel [1 ]
Dietz, Alina [1 ]
Garza, Celeste [1 ]
Moy, Brian [1 ]
Crisostomo, Neil Elijah S. [1 ]
Vukmirovic, Dora [1 ]
Forsthuber, Thomas [1 ]
机构：
[1] Univ Texas San Antonio, San Antonio, TX USA
来源：
JOURNAL OF IMMUNOLOGY | 2020年 / 204卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
230.15
引用
收藏
页数：2
相关论文
共 42 条
  • [21] T-cell vaccination leads to suppression of intrapancreatic Th17 cells through Stat3-mediated RORγt inhibition in autoimmune diabetes
    Min Wang
    Liu Yang
    Xiaoyan Sheng
    Weilei Chen
    Haiqing Tang
    Hongguang Sheng
    Beili Xi
    Ying Qin Zang
    Cell Research, 2011, 21 : 1358 - 1369
  • [22] T-bet represses collagen-induced arthritis by suppressing Th17 lineage commitment through inhibition of RORγt expression and function
    Shimizu, Masaru
    Kondo, Yuya
    Tanimura, Reona
    Furuyama, Kotona
    Yokosawa, Masahiro
    Asashima, Hiromitsu
    Tsuboi, Hiroto
    Matsumoto, Isao
    Sumida, Takayuki
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [23] T-bet represses collagen-induced arthritis by suppressing Th17 lineage commitment through inhibition of RORγt expression and function
    Masaru Shimizu
    Yuya Kondo
    Reona Tanimura
    Kotona Furuyama
    Masahiro Yokosawa
    Hiromitsu Asashima
    Hiroto Tsuboi
    Isao Matsumoto
    Takayuki Sumida
    Scientific Reports, 11
  • [24] Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-γ production by memory CD4+ T cells
    Napolitani, Giorgio
    Acosta-Rodriguez, Eva V.
    Lanzavecchia, Antonio
    Sallusto, Federica
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2009, 39 (05) : 1301 - 1312
  • [25] Timosaponin A-III Alleviates Asthma-Induced Airway Inflammation, Th17 Cell Differentiation, and STAT3/RORγt Pathway
    Wang, Lijie
    Yuan, Jiabo
    Zhao, Ruiqi
    Wang, Congyao
    Li, Zhuying
    IMMUNOLOGICAL INVESTIGATIONS, 2025,
  • [26] Novel benzenediamine derivative FC99 ameliorates zymosan-induced arthritis by inhibiting RORγt expression and Th17 cell differentiation
    Ji, Jianjian
    Dou, Huan
    Li, Xiaoqin
    Song, Yuxian
    Li, Xiaojing
    Li, Erguang
    Tan, Renxiang
    Hou, Yayi
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2014, 46 (10) : 829 - 836
  • [27] p300 promotes differentiation of Th17 cells via positive regulation of the nuclear transcription factor RORγt in acute respiratory distress syndrome
    Chen, Yan
    Wang, Daoxin
    Zhao, Yan
    Huang, Bin
    Cao, Haiquan
    Qi, Di
    IMMUNOLOGY LETTERS, 2018, 202 : 8 - 15
  • [28] Exogenous IFN-γ ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cells
    Feng, Gang
    Gao, Wenda
    Strom, Terry B.
    Oukka, Mohamed
    Francis, Ross S.
    Wood, Kathryn J.
    Bushell, Andrew
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2008, 38 (09) : 2512 - 2527
  • [29] Ursolic acid inhibits Th17 cell differentiation via STAT3/RORγt pathway and suppresses Schwann cell-mediated Th17 cell migration by reducing CXCL9/10 expression
    Xu, Hua
    Yu, Ai-Ling
    Zhao, Da-Peng
    Meng, Guang-Yuan
    Wang, Ling
    Shan, Min
    Hu, Nai-Xia
    Liu, Yun-Lin
    INNATE IMMUNITY, 2022, 28 (05) : 155 - 163
  • [30] IL-21 induction of CD4+T cell differentiation into Th17 cells contributes to bleomycin-induced fibrosis in mice
    Lei, Ling
    Zhong, Xiao-Ning
    He, Zhi-Yi
    Zhao, Cheng
    Sun, Xue-Jiao
    CELL BIOLOGY INTERNATIONAL, 2015, 39 (04) : 388 - 399
12345