Epidemiology of oral human papillomavirus infection

被引:99
作者
Chung, Christine H. [1 ,2 ]
Bagheri, Ashley [1 ]
D'Souza, Gypsyamber [3 ]
机构
[1] Johns Hopkins Med Inst, Dept Oncol, Baltimore, MD 21205 USA
[2] Johns Hopkins Med Inst, Dept Otolaryngol Head & Neck Surg, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD 21205 USA
[3] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA
关键词
Human papillomavirus; Oral infection; Oropharynx cancer; Prevalence; Incidence; Natural history; GENITAL HUMAN-PAPILLOMAVIRUS; CERVICAL HPV INFECTION; NATURAL-HISTORY; CANCER INCIDENCE; RISK-FACTORS; UNITED-STATES; HEAD; PREVALENCE; OROPHARYNGEAL; TONSILLAR;
D O I
10.1016/j.oraloncology.2013.09.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objective: To describe what is known about the epidemiology of oral human papillomavirus (HPV) infection. Methods: In this article we review current data on HPV prevalence, natural history, mode of acquisition, and risk factors for oral HPV infection. Results & Conclusion: Over the past several years new studies have informed our understanding of oral HPV infection. These data suggest oral HPV prevalence is higher in men than women and support the sexual transmission of HPV to the mouth by oral sex. Data is emerging suggesting that most oral HPV infections usually clear within a year on and describing risk factors for prevalent and persistent infection. Recent data support likely efficacy of the HPV vaccine for oral HPV, suggesting vaccination may reduce risk of HPV-related oropharyngeal cancer. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:364 / 369
页数:6
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