Bortezomib-induced painful neuropathy in patients with multiple myeloma

被引：17
作者：
Bilinska, Malgorzata [1 ]
Usnarska-Zubkiewicz, Lidia [2 ]
Pokryszko-Dragan, Anna [1 ]
机构：
[1] Wroclaw Med Univ, Dept Neurol, Wroclaw, Poland
[2] Wroclaw Med Univ, Dept Haematol Blood Neoplasms & Bone Marrow Trans, Wroclaw, Poland
来源：
WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY | 2013年 / 17卷 / 05期
关键词：
multiple myeloma; bortezomib; bortezomib induced neuropathy; PERIPHERAL NEUROPATHY; DIABETIC-NEUROPATHY; REFRACTORY MYELOMA; CONTROLLED-TRIAL; DOUBLE-BLIND; HUMAN-SKIN; NEUROTOXICITY; REVERSIBILITY; EXPERIENCE; EFFICACY;
D O I：
10.5114/wo.2013.37214
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Neurotoxicity towards the peripheral nervous system which appears clinically in the form of painful neuropathy is an essential dose-limiting factor during the treatment of multiple myeloma. In this review article different forms of this painful neuropathy are presented together with currently available diagnostic tools which are usually applied to confirm the diagnosis. Also, the most often used neurological scales estimating neurological deficit are presented. Special attention is paid to the management of the reversibility of bortezomib-induced neuropathic pain.
引用
收藏
页码：421 / 426
页数：6
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