Synthesis of model compound containing an indole spiro-β-lactam moiety with vinylchloride in chartellines

被引：49

作者：

Nishikawa, T ^{[1
]}

Kajii, S ^{[1
]}

Isobe, M ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Bioagr Sci, Organ Chem Lab, Nagoya, Aichi 4648601, Japan

来源：

CHEMISTRY LETTERS | 2004年 / 33卷 / 04期

关键词：

D O I：

10.1246/cl.2004.440

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A model compound containing an indole beta-lactam moiety hearing vinylchloride in chartellines was synthesized from the Mannich reaction of isatin imine with ketene silyl acetal, beta-lactam formation of the resulting beta-amino ester, and copper(I)mediated coupling with (E)-alpha-chloro-beta-iodostyrene.

引用

页码：440 / 441

页数：2

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