A 12-month randomized controlled trial evaluating erythritol air-polishing versus curette/ultrasonic debridement of mandibular furcations in supportive periodontal therapy

被引:17
作者
Ulvik, Ingvild M. [1 ]
Saethre, Terje [1 ]
Bunaes, Dagmar F. [1 ]
Lie, Stein Atle [1 ]
Enersen, Morten [2 ]
Leknes, Knut N. [1 ]
机构
[1] Univ Bergen, Dept Clin Dent, Fac Med, Aarstadveien 19, N-5009 Bergen, Norway
[2] Univ Oslo, Inst Oral Biol, Fac Dent, Oslo, Norway
关键词
Air-polishing; Erythritol; Furcation involvement; Periodontal maintenance; Visual analogue scale;
D O I
10.1186/s12903-021-01397-3
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Background Due to complex morphology and limited access, the cleaning of the furcation area is extremely challenging. Therefore, novel therapeutic approaches need to be tested to potentially overcome debridement limitations. The aim of the present prospective 12-month study was to compare clinical and microbiological effects following erythritol air-polishing versus conventional mechanical debridement of furcation defects in a cohort of periodontal maintenance patients. Methods Twenty patients with grade II mandibular molar furcation defects volunteered to enroll in this single-centre, examiner masked, randomized controlled trial. In a split-mouth study design, two furcation sites in each patient were randomly assigned to either receive subgingival debridement using erythritol air-polishing (test) or conventional ultrasonic/curette debridement (control) at baseline, and at 3, 6, 9 and 12 months. Probing depth, clinical attachment level and bleeding on probing were recorded at 3-month intervals. Subgingival microbiological samples obtained at baseline, 6 and 12 months were analyzed using checkerboard DNA-DNA hybridization. Discomfort from treatment was scored at 12 months using a visual analogue scale. The differences between treatments, and time-points, were tested using multilevel analysis (mixed effect models and robust variance estimates). Results A significant reduction in probing depth took place following both treatments (p < 0.001). Control sites experienced a significant mean gain in clinical attachment level of 0.5 mm (0.2) (p=0.004), whereas a non-significant gain of 0.4 mm (0.3) was observed at test sites (p=0.119). At 6 months, a significant between-treatment difference of 0.8 mm (+/- 0.4) was observed in favor of the control (p=0.032). No significant between-treatment differences were observed in microbial load or composition. Notably, at 12 months patients experienced significantly less discomfort following air-polishing compared with control (p=0.001). Conclusions The 12-month observations indicate that erythritol air-polishing and conventional mechanical debridement both support clinical improvements. A significant between-treatment difference in clinical attachment level was, however, detected in favour of control debridement at 6 months. In terms of patient comfort, erythritol air-polishing is superior. Trial Registration: The clinical trial was retrospectively registered in ClinicalTrial.gov with registration NCT04493398 (07/28/2020).
引用
收藏
页数:11
相关论文
共 55 条
  • [1] SPLIT-MOUTH AND CROSS-OVER DESIGNS IN DENTAL RESEARCH
    ANTCZAKBOUCKOMS, AA
    TULLOCH, JFC
    BERKEY, CS
    [J]. JOURNAL OF CLINICAL PERIODONTOLOGY, 1990, 17 (07) : 446 - 453
  • [2] Armitage G C, 1999, Ann Periodontol, V4, P1, DOI 10.1902/annals.1999.4.1.1
  • [3] Analysis of gingival crevice fluid and risk of progression of periodontitis
    Armitage, GC
    [J]. PERIODONTOLOGY 2000, 2004, 34 : 109 - 119
  • [4] EFFECT OF NONSURGICAL PERIODONTAL THERAPY .2. SEVERELY ADVANCED PERIODONTITIS
    BADERSTEN, A
    NILVEUS, R
    EGELBERG, J
    [J]. JOURNAL OF CLINICAL PERIODONTOLOGY, 1984, 11 (01) : 63 - 76
  • [5] Gingival crevicular fluid as a source of biomarkers for periodontitis
    Barros, Silvana P.
    Williams, Ray
    Offenbacher, Steven
    Morelli, Thiago
    [J]. PERIODONTOLOGY 2000, 2016, 70 (01) : 53 - 64
  • [6] The Impact of the Stone Age Diet on Gingival Conditions in the Absence of Oral Hygiene
    Baumgartner, Stefan
    Imfeld, Thomas
    Schicht, Olivier
    Rath, Christian
    Persson, Rigmor E.
    Persson, G. Rutger
    [J]. JOURNAL OF PERIODONTOLOGY, 2009, 80 (05) : 759 - 768
  • [7] Molecular microbiological evaluation of subgingival biofilm sampling by paper point and curette
    Belibasakis, Georgios N.
    Schmidlin, Patrick R.
    Sahrmann, Philipp
    [J]. APMIS, 2014, 122 (04) : 347 - 352
  • [8] FURCATION MORPHOLOGY RELATIVE TO PERIODONTAL TREATMENT - FURCATION ROOT SURFACE ANATOMY
    BOWER, RC
    [J]. JOURNAL OF PERIODONTOLOGY, 1979, 50 (07) : 366 - 374
  • [10] The effect of smoking on inflammatory and bone remodeling markers in gingival crevicular fluid and subgingival microbiota following periodontal therapy
    Bunaes, D. F.
    Mustafa, M.
    Mohamed, H. G.
    Lie, S. A.
    Leknes, K. N.
    [J]. JOURNAL OF PERIODONTAL RESEARCH, 2017, 52 (04) : 713 - 724