Impact of Induced Pluripotent Stem Cells in Bone Repair and Regeneration

被引：32
|
作者：
Rana, Deepti [1 ]
Kumar, Sanjay [2 ]
Webster, Thomas J. [3 ]
Ramalingam, Murugan [4 ]
机构：
[1] Univ Twente, Tech Med Ctr, Dept Biomech Engn, NL-7522 NB Enschede, Netherlands
[2] Christian Med Coll Campus, Ctr Stem Cell Res, Vellore 632002, Tamil Nadu, India
[3] Northeastern Univ, Dept Chem Engn, Boston, MA 02115 USA
[4] Deemed Univ, Vellore Inst Technol, Ctr Biomat Cellular & Mol Theranost, Biomat & Stem Cell Engn Lab,Sch Mech Engn, Vellore 632014, Tamil Nadu, India
来源：
CURRENT OSTEOPOROSIS REPORTS | 2019年 / 17卷 / 04期
关键词：
Induced pluripotent stem cells (iPSCs); Biomaterials; Osteogenic differentiation; Bone tissue engineering; Bone regeneration; CALCIUM-PHOSPHATE SCAFFOLD; TISSUE; BIOMATERIALS; DESIGN; DEFECT;
D O I：
10.1007/s11914-019-00519-9
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Purpose of ReviewThe main objective of this article is to investigate the current trends in the use of induced pluripotent stem cells (iPSCs) for bone tissue repair and regeneration.Recent FindingsPluripotent stem cell-based tissue engineering has extended innovative therapeutic approaches for regenerative medicine. iPSCs have shown osteogenic differentiation capabilities and would be an innovative resource of stem cells for bone tissue regenerative applications.SummaryThis review recapitulates the current knowledge and recent progress regarding utilization of iPSCs for bone therapy. A review of current findings suggests that a combination of a three-dimensional scaffolding system with iPSC technology to mimic the physiological complexity of the native stem cell niche is highly favorable for bone tissue repair and regeneration.
引用
收藏
页码：226 / 234
页数：9
相关论文
共 50 条
  • [31] Potential of Induced Pluripotent Stem Cells for the Regeneration of the Tracheal Wall
    Imaizumi, Mitsuyoshi
    Nomoto, Yukio
    Sugino, Takashi
    Miyake, Masao
    Wada, Ikuo
    Nakamura, Tatsuo
    Omori, Koichi
    ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2010, 119 (10): : 697 - 703
  • [32] Kidney regeneration from human induced pluripotent stem cells
    Mae, Shin-Ichi
    Osafune, Kenji
    CURRENT OPINION IN ORGAN TRANSPLANTATION, 2015, 20 (02) : 171 - 177
  • [33] Stability and safety of induced pluripotent stem cells for cartilage regeneration
    Poulou, M.
    Papathanasiou, I.
    Mourmoura, E.
    Brantzos, T.
    Sfougataki, I.
    Mertzanian, A.
    Goussetis, E.
    Trachana, V.
    Tsezou, A.
    Tzetis, M.
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2020, 28 (SUPPL 1) : 763 - 763
  • [34] Bone regeneration of induced pluripotent stem cells derived from peripheral blood cells in collagen sponge scaffolds
    Kato, Hiroshi
    Watanabe, Katsuhito
    Saito, Akiko
    Onodera, Shoko
    Azuma, Toshifumi
    Takano, Masayuki
    JOURNAL OF APPLIED ORAL SCIENCE, 2022, 30
  • [35] Utilization of Human Induced Pluripotent Stem Cells for Cardiac Repair
    Fan, Chengming
    Zhang, Eric
    Joshi, Jyotsna
    Yang, Jinfu
    Zhang, Jianyi
    Zhu, Wuqiang
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 8
  • [36] Stem cell therapy in liver regeneration: Focus on mesenchymal stem cells and induced pluripotent stem cells
    Zhang, Lu
    Ma, Xiao-Jing-Nan
    Fei, Yuan-Yuan
    Han, Heng-Tong
    Xu, Jun
    Cheng, Lu
    Li, Xun
    PHARMACOLOGY & THERAPEUTICS, 2022, 232
  • [37] The impact of induced pluripotent stem cells in animal conservation
    Yurou Wu
    Chengwei Wang
    Xinyun Fan
    Yuxiao Ma
    Zibo Liu
    Xun Ye
    Chongyang Shen
    Chunjie Wu
    Veterinary Research Communications, 2024, 48 : 649 - 663
  • [38] The impact of induced pluripotent stem cells in animal conservation
    Wu, Yurou
    Wang, Chengwei
    Fan, Xinyun
    Ma, Yuxiao
    Liu, Zibo
    Ye, Xun
    Shen, Chongyang
    Wu, Chunjie
    VETERINARY RESEARCH COMMUNICATIONS, 2024, 48 (02) : 649 - 663
  • [39] Exploring the application of mesenchymal stem cells in bone repair and regeneration
    Griffin, M.
    Iqbal, S. A.
    Bayat, A.
    JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2011, 93B (04): : 427 - 434
  • [40] Mesenchymal stem cells and their involvement in bone remodeling, repair, and regeneration
    Heersche, JNM
    AGING, OSTEOPOROSIS, AND DENTAL IMPLANTS, 2002, : 17 - 23
12345