Phase transitions in systems with two species of molecular motors

被引:67
作者
Klumpp, S [1 ]
Lipowsky, R [1 ]
机构
[1] Max Planck Inst Colloids & Interfaces, D-14424 Potsdam, Germany
来源
EUROPHYSICS LETTERS | 2004年 / 66卷 / 01期
关键词
D O I
10.1209/epl/i2003-10155-6
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
Systems with two species of active molecular motors moving on (cytoskeletal) filaments into opposite directions are studied theoretically using driven lattice gas models. The motors can unbind from and rebind to the filaments. Two motors are more likely to bind on adjacent filament sites if they belong to the same species. These systems exhibit i) continuous phase transitions towards states with spontaneously broken symmetry, where one motor species is largely excluded from the filament, ii) hysteresis of the total current upon varying the relative concentrations of the two motor species, and iii) coexistence of traffic lanes with opposite directionality in multi-filament systems. These theoretical predictions should be experimentally accessible.
引用
收藏
页码:90 / 96
页数:7
相关论文
共 19 条
[1]  
[Anonymous], 2001, MECH MOTOR PROTEINS
[2]   Shock formation in an exclusion process with creation and annihilation -: art. no. 026117 [J].
Evans, MR ;
Juhász, R ;
Santen, L .
PHYSICAL REVIEW E, 2003, 68 (02) :8
[3]   SPONTANEOUS SYMMETRY-BREAKING IN A ONE-DIMENSIONAL DRIVEN DIFFUSIVE SYSTEM [J].
EVANS, MR ;
FOSTER, DP ;
GODRECHE, C ;
MUKAMEL, D .
PHYSICAL REVIEW LETTERS, 1995, 74 (02) :208-211
[4]   Reversal in the direction of movement of a molecular motor [J].
Henningsen, U ;
Schliwa, M .
NATURE, 1997, 389 (6646) :93-96
[5]   Traffic of molecular motors through tube-like compartments [J].
Klumpp, S ;
Lipowsky, R .
JOURNAL OF STATISTICAL PHYSICS, 2003, 113 (1-2) :233-268
[6]  
KLUMPP S, UNPUB
[7]   Long-range order in a quasi one-dimensional non-equilibrium three-state lattice gas [J].
Korniss, G ;
Schmittmann, B ;
Zia, RKP .
EUROPHYSICS LETTERS, 1999, 45 (04) :431-436
[8]   BOUNDARY-INDUCED PHASE-TRANSITIONS IN DRIVEN DIFFUSIVE SYSTEMS [J].
KRUG, J .
PHYSICAL REVIEW LETTERS, 1991, 67 (14) :1882-1885
[9]   Random walks of cytoskeletal motors in open and closed compartments [J].
Lipowsky, R ;
Klumpp, S ;
Nieuwenhuizen, TM .
PHYSICAL REVIEW LETTERS, 2001, 87 (10) :art. no.-108101
[10]   KINESIN AND NCD BIND THROUGH A SINGLE HEAD TO MICROTUBULES AND COMPETE FOR A SHARED MT BINDING-SITE [J].
LOCKHART, A ;
CREVEL, IMTC ;
CROSS, RA .
JOURNAL OF MOLECULAR BIOLOGY, 1995, 249 (04) :763-771