Multi-frequency electrical impedance tomography and neuroimaging data in stroke patients

被引:64
|
作者
Goren, Nir [1 ]
Avery, James [1 ]
Dowrick, Thomas [1 ]
Mackle, Eleanor [1 ]
Witkowska-Wrobel, Anna [1 ]
Werring, David [2 ]
Holder, David [1 ]
机构
[1] UCL, Med Phys & Biomed Engn, London WC1E 6BT, England
[2] UCL, Inst Neurol, Dept Brain Repair & Rehabil, Stroke Res Ctr, London WC1N 3BG, England
基金
英国工程与自然科学研究理事会;
关键词
ACUTE ISCHEMIC-STROKE; RECONSTRUCTION ALGORITHMS; BRAIN; SYSTEM; MODEL; EIT; EEG;
D O I
10.1038/sdata.2018.112
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Electrical Impedance Tomography (EIT) is a non-invasive imaging technique, which has the potential to expedite the differentiation of ischaemic or haemorrhagic stroke, decreasing the time to treatment. Whilst demonstrated in simulation, there are currently no suitable imaging or classification methods which can be successfully applied to human stroke data. Development of these complex methods is hindered by a lack of quality Multi-Frequency EIT (MFEIT) data. To address this, MFEIT data were collected from 23 stroke patients, and 10 healthy volunteers, as part of a clinical trial in collaboration with the Hyper Acute Stroke Unit (HASU) at University College London Hospital (UCLH). Data were collected at 17 frequencies between 5 Hz and 2 kHz, with 31 current injections, yielding 930 measurements at each frequency. This dataset is the most comprehensive of its kind and enables combined analysis of MFEIT, Electroencephalography (EEG) and Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) data in stroke patients, which can form the basis of future research into stroke classification.
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页数:10
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