Cell culture of retinal pigment epithelium: Special Issue

被引：42

作者：

Pfeffer, Bruce A. ^{[1
,2
,3
,4
]}

Philp, Nancy J. ^{[5
]}

机构：

[1] Vet Affairs Western New York Healthcare Syst, Buffalo, NY 14215 USA

[2] SUNY Buffalo, Dept Ophthalmol, Ross Eye Inst, Buffalo, NY 14215 USA

[3] SUNY Buffalo, Dept Biochem, Buffalo, NY 14215 USA

[4] SUNY Buffalo, SUNY Eye Inst, Buffalo, NY 14215 USA

[5] Thomas Jefferson Univ, Dept Pathol Anat & Cell Biol, Philadelphia, PA 19107 USA

来源：

EXPERIMENTAL EYE RESEARCH | 2014年 / 126卷

关键词：

retinal pigment epithelium; cell culture; translational ophthalmology; in vitro models; ocular cell lines; cell differentiation; signature genes; TISSUE-CULTURE; RPE CELLS; GROWTH-CHARACTERISTICS; IN-VITRO; HETEROGENEITY; ARPE-19; PROTEIN; VIVO;

D O I：

10.1016/j.exer.2014.07.010

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

This series of review articles highlights how in vitro models of RPE can be effectively used to understand essential functions of the RPE that are not only fundamental to epithelial biology, but also have direct relevance to the visual system. The issue contains reviews from experts in the field covering aspects of basic cell and epithelial biology, namely: the barrier properties of the RPE (Rizzolo, 2014), epithelial polarity (Lehmann et al., 2014), cytoskeleton (Bonilha, 2014), and lysosomes (Guha et al., 2014), as well as properties more unique to the RPE, e.g., vitamin A metabolism (Hu and Bok, 2014), bioenergetics (Adijanto and Philp, 2014), phagocytosis (Mazzoni et al., 2014), ion transport (Reichhart and Strata 2014), and melanin/lipofuscin (Boulton, 2014). (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：1 / 4

页数：4

共 39 条

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