Profile of SARS-CoV-2

被引:4
作者
Heinz, Franz X. [1 ]
Stiasny, Karin [1 ]
机构
[1] Med Univ Vienna, Ctr Virol, Kinderspitalgasse 15, A-1090 Vienna, Austria
关键词
COVID-19; Coronavirus; Origin and evolution; Vaccines; Antivirals; COVID-19; SPIKE;
D O I
10.1007/s00508-020-01763-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The recent emergence of a new coronavirus (severe acute respiratory syndrome corona-virus-2, SARS-CoV-2) that is transmitted efficiently among humans and can result in serious disease and/or death has become a global threat to public health and economy. In this article, we describe some of the most important characteristics of this new virus (including gaps in our understanding) and provide a perspective of ongoing activities for developing virus-specific countermeasures, such as vaccines and antiviral drugs.
引用
收藏
页码:635 / 644
页数:10
相关论文
共 91 条
[91]   Potently neutralizing and protective human antibodies against SARS-CoV-2 [J].
Zost, Seth J. ;
Gilchuk, Pavlo ;
Case, James Brett ;
Binshtein, Elad ;
Chen, Rita E. ;
Nkolola, Joseph P. ;
Schafer, Alexandra ;
Reidy, Joseph X. ;
Trivette, Andrew ;
Nargi, Rachel S. ;
Sutton, Rachel E. ;
Suryadevara, Naveenchandra ;
Martinez, David R. ;
Williamson, Lauren E. ;
Chen, Elaine C. ;
Jones, Taylor ;
Day, Samuel ;
Myers, Luke ;
Hassan, Ahmed O. ;
Kafai, Natasha M. ;
Winkler, Emma S. ;
Fox, Julie M. ;
Shrihari, Swathi ;
Mueller, Benjamin K. ;
Meiler, Jens ;
Chandrashekar, Abishek ;
Mercado, Noe B. ;
Steinhardt, James J. ;
Ren, Kuishu ;
Loo, Yueh-Ming ;
Kallewaard, Nicole L. ;
McCune, Broc T. ;
Keeler, Shamus P. ;
Holtzman, Michael J. ;
Barouch, Dan H. ;
Gralinski, Lisa E. ;
Baric, Ralph S. ;
Thackray, Larissa B. ;
Diamond, Michael S. ;
Carnahan, Robert H. ;
Crowe, James E., Jr. .
NATURE, 2020, 584 (7821) :443-+