A Universal Approach to Ultrasmall Magneto-Fluorescent Nanohybrids

被引：25

作者：

Feld, Artur ^{[1
]}

Merkl, Jan-Philip ^{[1
]}

Kloust, Hauke ^{[1
]}

Flessau, Sandra ^{[1
]}

Schmidtke, Christian ^{[1
]}

Wolter, Christopher ^{[1
]}

Ostermann, Johannes ^{[1
,2
]}

Kampferbeck, Michael ^{[1
]}

Eggers, Robin ^{[1
]}

Mews, Alf ^{[1
,2
]}

Schotten, Theo ^{[2
]}

Weller, Horst ^{[1
,2
,3
]}

机构：

[1] Univ Hamburg, Inst Phys Chem, D-20146 Hamburg, Germany

[2] Ctr Appl Nanotechnol, D-20146 Hamburg, Germany

[3] Univ Hamburg, Hamburg Ctr Ultrafast Imaging, D-22761 Hamburg, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 42期

关键词：

emulsion polymerization; magnetofluorescence; nanocomposites; nanohybrids; single-particle spectroscopy; IRON-OXIDE NANOPARTICLES; QUANTUM DOTS; BIOLOGICAL APPLICATIONS; HYBRID NANOPARTICLES; LIGAND SHELL; IN-VITRO; SEMICONDUCTOR; NANOCOMPOSITES; NANOCRYSTALS; PROBES;

D O I：

10.1002/anie.201503017

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Seeded emulsion polymerization is a powerful universal method to produce ultrasmall multifunctional magnetic nanohybrids. In a two-step procedure, iron oxide nanocrystals were initially encapsulated in a polystyrene (PS) shell and subsequently used as beads for a controlled assembly of elongated quantum dots/quantum rods (QDQRs). The synthesis of a continuous PS shell allows the whole construct to be fixed and the composition of the nanohybrid to be tuned. The fluorescence of the QDQRs and magnetism of iron oxide were perfectly preserved, as confirmed by single-particle investigation, fluorescence decay measurements, and relaxometry. Biofunctionalization of the hybrids was straightforward, involving copolymerization of appropriate affinity ligands as shown by immunoblot analysis. Additionally, the universality of this method was shown by the embedment of a broad scale of NPs.

引用

页码：12468 / 12471

页数：4

共 40 条

[1] Fluorescent, magnetic and plasmonic-Hybrid multifunctional colloidal nano objects [J].