Obstructive Sleep Apnea Among Obese Patients With Type 2 Diabetes

被引:412
|
作者
Foster, Gary D. [1 ]
Sanders, Mark H. [2 ]
Millman, Richard [3 ]
Zammit, Gary [4 ]
Borradaile, Kelley E. [1 ]
Newman, Anne B. [2 ]
Wadden, Thomas A. [2 ,5 ]
Kelley, David
Wing, Rena R. [3 ]
Sunyer, F. Xavier Pi [6 ]
Darcey, Valerie [5 ]
Kuna, Samuel T. [5 ]
机构
[1] Temple Univ, Philadelphia, PA 19122 USA
[2] Univ Pittsburgh, Pittsburgh, PA USA
[3] Brown Univ, Providence, RI 02912 USA
[4] Clinilabs, New York, NY USA
[5] Univ Penn, Philadelphia, PA 19104 USA
[6] Columbia Univ, New York, NY USA
关键词
CYSTIC-FIBROSIS; MELLITUS;
D O I
10.2337/dc08-1776
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE - To assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among obese patients with type 2 diabetes. RESEARCH DESIGN AND METHODS - Unattended polysomnography was performed in 306 participants. RESULTS - Over 86% of participants had OSA with an apnea-hypopnea index (AHI) >= 5 events/h. The mean AHI was 20.5 +/- 16.8 events/h. A total of 30.5% of the participants had moderate OSA (1.5 <= AHI <30), and 22.6% had severe OSA (AHI >= 30). Waist circumference (odds ratio 1.1; 95% CL 1.0-1.1.; P = 0.03) was significantly related to the presence of OSA. Severe OSA was most likely in individuals with a higher BMI (odds ratio 1.1; 95% Cl 1..0-1.2; P = 0.03). CONCLUSIONS - Physicians should be particularly cognizant of the likelihood of OSA in obese patients with type 2 diabetes, especially among individuals with higher waist. circumference and BMI. Diabetes Care 32:1.0.1.7-1019, 2009
引用
收藏
页码:1017 / 1022
页数:6
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