Functionalized sulfur-containing compounds.: 13.: Synthesis of substituted 3-amino-2-(organylsulfinyl)- and -(organylsulfonyl)thieno[2,3-b]pyridines

被引：7

作者：

Kalugin, V. E. ^{[1
]}

Shestopalov, A. M. ^{[1
]}

Litvinov, V. P. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinskii Organ Chem Inst, Moscow 119991, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2006年 / 55卷 / 03期

关键词：

intramolecular cyclization; the Thorpe-Ziegler reaction; 3-cyanopyridine-2-thiones; chloromethyl organyl sulfides; chloromethyl organyl sulfones; 3-cyano-2-[(organylsulfinyl)methylthio]pyridines; 3-amino-2-(organylsulfinyl)thieno[2,3-b]pyridines; 3-amino2-(organylsulfonyl)thieno[2,3-b]pyridines;

D O I：

10.1007/s11172-006-0287-y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A method for the synthesis of substituted 3-amino-2-(organylsulfinyl)thieno[2,3-b]pyridines by the Thorpe-Ziegler intramolecular cyclization of substituted 3-cyano-2-[(organylsulfinyl)methylthio]pyridines was proposed. 3-Amino-2-(organylsulfonyl)thieno [ 2,3-b] pyridines were obtained by reactions of substituted 3-cyanopyridine-2-thiones with chloromethyl organyl sulfones. The reaction intermediates 3-cyano-2-[(organylsulfonyl)methylthio]pyridines were transformed into 3-amino-2-(organylsulfonyl)thieno [2,3-b] pyridines.

引用

页码：529 / 534

页数：6

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