The Cell Biology of HIV-1 Virion Genesis

被引：152

作者：

Bieniasz, Paul D. ^{[1
,2
]}

机构：

[1] Aaron Diamond AIDS Res Ctr, Howard Hughes Med Inst, New York, NY 10016 USA

[2] Rockefeller Univ, Lab Retrovirol, New York, NY 10065 USA

来源：

CELL HOST & MICROBE | 2009年 / 5卷 / 06期

关键词：

VIRUS TYPE-1 GAG; ESCRT-III COMPLEX; PLASMA-MEMBRANE; VPU PROTEIN; MATRIX PROTEIN; PARTICLE RELEASE; STRUCTURAL BASIS; INHIBITS HIV-1; LIVING CELLS; LIVE CELLS;

D O I：

10.1016/j.chom.2009.05.015

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Recent work has illuminated three critical aspects of the cell biology of HIV-1 particle genesis. First, we have come to understand which cellular membranes are selected as platforms for virus particle assembly and how this occurs. Second, an understanding of how the host ESCRT pathway enables virion budding is accruing. Third, it has become apparent that a host inhibitor can block HIV-1 particle release and that antagonism of this inhibitor underlies the ability of HIV and SIV accessory genes to facilitate particle release. Here, I review recent progress in these three areas.

引用

页码：550 / 558

页数：9

共 71 条

[1]

Adamson CS, 2007, ADV PHARMACOL, V55, P347, DOI 10.1016/S1054-3589(07)55010-6

[2] Quantitative membrane proteomics reveals new cellular targets of viral immune modulators [J].

Bartee, Eric ;

McCormack, Ashley ;

Fruh, Klaus .

PLOS PATHOGENS, 2006, 2 (10) :975-988

[3] Late budding domains and host proteins in enveloped virus release [J].

Bieniasz, PD .

VIROLOGY, 2006, 344 (01) :55-63

[4] Modulation of HIV-like particle assembly in vitro by inositol phosphates [J].

Campbell, S ;

Fisher, RJ ;

Towler, EM ;

Fox, S ;

Issaq, HJ ;

Wolfe, T ;

Phillips, LR ;

Rein, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (19) :10875-10879

[5] Parallels between cytokinesis and retroviral budding: A role for the ESCRT machinery [J].

Carlton, Jez G. ;

Martin-Serrano, Juan .

SCIENCE, 2007, 316 (5833) :1908-1912

[6] Interaction between the human immunodeficiency virus type 1 Gag matrix domain and phosphatidylinositol-(4,5)-bisphosphate is essential for efficient Gag membrane binding [J].

Chukkapalli, Vineela ;

Hogue, Ian B. ;

Boyko, Vitaly ;

Hu, Wei-Shau ;

Ono, Akira .

JOURNAL OF VIROLOGY, 2008, 82 (05) :2405-2417

[7] NEDD4L overexpression rescues the release and infectivity of human immunodeficiency virus type 1 constructs lacking PTAP and YPXL late domains [J].

Chung, Hyo-Young ;

Morita, Eiji ;

von Schwedler, Uta ;

Mueller, Barbara ;

Kraeusslich, Hans-Georg ;

Sundquist, Wesley I. .

JOURNAL OF VIROLOGY, 2008, 82 (10) :4884-4897

[8] Interactions between HIV-1 Gag molecules in solution: An inositol phosphate-mediated switch [J].

Datta, Siddhartha A. K. ;

Zhao, Zhuojun ;

Clark, Patrick K. ;

Tarasov, Sergey ;

Alexandratos, Jerry N. ;

Campbell, Stephen J. ;

Kvaratskhelia, Mamuka ;

Lebowitz, Jacob ;

Rein, Alan .

JOURNAL OF MOLECULAR BIOLOGY, 2007, 365 (03) :799-811

[9] In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53 [J].

Denek, Magdalena ;

Pelchen-Matthews, Annegret ;

Byland, Rahel ;

Ruiz-Mateos, Ezequiel ;

Marsh, Mark .

JOURNAL OF CELL BIOLOGY, 2007, 177 (02) :329-341

[10] Suppression of Tetherin-Restricting Activity upon Human Immunodeficiency Virus Type 1 Particle Release Correlates with Localization of Vpu in the trans-Golgi Network [J].

Dube, Mathieu ;

Roy, Bibhuti Bhusan ;

Guiot-Guillain, Pierre ;

Mercier, Johanne ;

Binette, Julie ;

Leung, Grace ;

Cohen, Eric A. .

JOURNAL OF VIROLOGY, 2009, 83 (09) :4574-4590

← 1 2 3 4 5 6 7 8 →