Ultra-compliant neural probes are subject to fluid forces during dissolution of polymer delivery vehicles

被引：0

作者：

Rakuman, Wassim Ferose Habeeb ^{[1
]}

Ong, Xiao Chuan ^{[1
]}

Tetikol, H. Serhat ^{[1
]}

Khilwani, R. ^{[1
]}

Cui, X. Tracy ^{[2
]}

Ozdoganlar, O. Burak ^{[1
]}

Fedder, Gary K. ^{[1
]}

Gilgunn, Peter J. ^{[1
]}

机构：

[1] Carnegie Mellon Univ, Pittsburgh, PA 15217 USA

[2] Univ Pittsburgh, Pittsburgh, PA 15217 USA

来源：

2013 35TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) | 2013年

关键词：

BRAIN-TISSUE;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Ultra-compliant neural probes implanted into tissue using a molded, biodissolvable sodium carboxymethyl cellulose (Na-CMC)-saccharide composite needle delivery vehicle are subjected to fluid-structure interactions that can displace the recording site of the probe with respect to its designed implant location. We applied particle velocimetry to analyze the behavior of ultra-compliant structures under different implantation conditions for a range of CMC-based materials and identified a fluid management protocol that resulted in the successful targeted depth placement of the recording sites.

引用

页码：1550 / 1553

页数：4

共 4 条

[1] Ultra-miniature ultra-compliant neural probes with dissolvable delivery needles: design, fabrication and characterization
Khilwani, Rakesh
Gilgunn, Peter J.
Kozai, Takashi D. Y.
Ong, Xiao Chuan
Korkmaz, Emrullah
Gunalan, Pallavi K.
Cui, X. Tracy
Fedder, Gary K.
Ozdoganlar, O. Burak
BIOMEDICAL MICRODEVICES, 2016, 18 (06)
[2] Ultra-miniature ultra-compliant neural probes with dissolvable delivery needles: design, fabrication and characterization
Rakesh Khilwani
Peter J. Gilgunn
Takashi D. Y. Kozai
Xiao Chuan Ong
Emrullah Korkmaz
Pallavi K. Gunalan
X. Tracy Cui
Gary K. Fedder
O. Burak Ozdoganlar
Biomedical Microdevices, 2016, 18
[3] A transfer process to fabricate ultra-compliant neural probes in dissolvable needles
Ong, Xiao Chuan
Khilwani, Rakesh
Forssell, Mats
Ozdoganlar, O. Burak
Fedder, Gary K.
JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2017, 27 (03)
[4] AN ULTRA-COMPLIANT, SCALABLE NEURAL PROBE WITH MOLDED BIODISSOLVABLE DELIVERY VEHICLE
Gilgunn, P. J.
Khilwani, R.
Kozai, T. D. Y.
Weber, D. J.
Cui, X. T.
Erdos, G.
Ozdoganlar, O. B.
Fedder, G. K.
2012 IEEE 25TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS), 2012,

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