Montelukast in guidelines and beyond

被引：21
作者：
Bousquet, Jean [1 ]
Demoly, Pascal [1 ,2 ]
Humbert, Marc [3 ]
机构：
[1] Hop Arnaud Villeneuve, Serv Malad Resp, F-34275 Montpellier 5, France
[2] INSERM, U657, F-75654 Paris 13, France
[3] Univ Paris 11, Hop Antoine Beclere, Clamart, France
来源：
ADVANCES IN THERAPY | 2009年 / 26卷 / 06期
关键词：
allergic rhinitis; asthma; guidelines; inhaled corticosteroids; montelukast; rhinitis; LEUKOTRIENE-RECEPTOR ANTAGONIST; SEASONAL ALLERGIC RHINITIS; TERM CLINICAL-TRIAL; INHALED CORTICOSTEROIDS; ASTHMA CONTROL; DOUBLE-BLIND; PRESCHOOL-CHILDREN; ORAL MONTELUKAST; MILD ASTHMA; PLACEBO;
D O I：
10.1007/s12325-009-0038-1
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
In all asthma guidelines, preventive anti-inflammatory treatment is essential in all patients with persistent asthma. Inhaled corticosteroids are the mainstay of treatment in the control of asthma, but other treatments may be used as a monotherapy in patients with mild asthma or as an add-on treatment in those with moderate-to-severe asthma. Leukotriene modifiers are the only validated preventive treatment for all age groups. This review discusses the place of montelukast, a leukotriene receptor antagonist, using guidelines and consensus reports on asthma and rhinitis: the US National Asthma Education and Prevention Program (NAEPP); the British Guideline on the Management of Asthma; the Global Initiative on Asthma (GINA); and Allergic Rhinitis and its Impact on Asthma (ARIA). This review includes new studies that have not yet been considered in guidelines.
引用
收藏
页码：575 / 587
页数：13
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