Solid-phase synthesis of hydrophobic peptides on 1,6-hexanediol diacrylate crosslinked polystyrene resin: Comparison with merrifield resin

被引：0

作者：

Arunan, C ^{[1
]}

Pillai, VNR ^{[1
]}

机构：

[1] Mahatma Gandhi Univ, Sch Chem Sci, Kottayam 686560, Kerala, India

来源：

PROTEIN AND PEPTIDE LETTERS | 1999年 / 6卷 / 06期

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel polymer support based on 1,6-hexanediol diacrylate and polystyrene was developed. The resin showed better solvation in solvents used for peptide synthesis than Merrifield resin. The synthetic utility of the new support has been illustrated with the synthesis of some hydrophobic peptides which have high affinity for aggregation. The yield and purity of the peptides were high compared to when Merrifield resin was used.

引用

页码：391 / 398

页数：8

共 50 条

[21] SYNTHESIS OF NBB-RESIN, A NEW POLYMER SUPPORT FOR THE SOLID-PHASE SYNTHESIS OF PROTECTED PEPTIDES
GIRALT, E
ALBERICIO, F
ANDREU, D
ERITJA, R
MARTIN, P
PEDROSO, E
ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA, 1981, 77 (02): : 120 - 125
[22] Merrifield Resin Supported Solid Phase Synthesis of 1-Amino-2,4-imidazolidinedione
Pei, Wen
Tao, Jinhai
Sun, Li
Sun, Mengzhan
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2009, 29 (02) : 265 - 268
[23] RAPID METHOD FOR PREPARATION OF AMINO-ACID RESIN ESTERS FOR MERRIFIELD SOLID-PHASE PEPTIDE-SYNTHESIS
MONAHAN, MW
GILON, C
BIOPOLYMERS, 1973, 12 (11) : 2513 - 2519
[24] A novel traceless solid phase tertiary amine synthesis based on Merrifield resin
Cai, JQ
Wathey, B
TETRAHEDRON LETTERS, 2001, 42 (07) : 1383 - 1385
[25] Solid-phase synthesis of homodetic cyclic peptides from Fmoc-MeDbz-resin
Monaim, Shimaa A. H. Abdel
Acosta, Gerardo A.
Royo, Miriam
El-Faham, Ayman
de la Torre, Beatriz G.
Albericio, Fernando
TETRAHEDRON LETTERS, 2018, 59 (18) : 1779 - 1782
[26] EFFECTS OF RESIN SWELLING AND SUBSTITUTION ON SOLID-PHASE SYNTHESIS
PUGH, KC
YORK, EJ
STEWART, JM
INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 1992, 40 (3-4): : 208 - 213
[27] Preparation of poly (ethylene glycol) acrylate grafted polystyrene resin for solid-phase peptide synthesis
Zhang, Rongyue
Li, Qiang
Zhang, Jing
Li, Juan
Ma, Guanghui
Su, Zhiguo
REACTIVE & FUNCTIONAL POLYMERS, 2012, 72 (10) : 773 - 780
[28] Solid-phase synthesis of oligoesters using a JandaJel™ resin
Brümmer, O
Clapham, B
Janda, KD
TETRAHEDRON LETTERS, 2001, 42 (12) : 2257 - 2259
[29] Solid-phase organic synthesis: A critical understanding of the resin
Vaino, AR
Janda, KD
JOURNAL OF COMBINATORIAL CHEMISTRY, 2000, 2 (06): : 579 - 596
[30] PhFl polystyrene: A new resin for solid phase organic synthesis
Bleicher, KH
Wareing, JR
TETRAHEDRON LETTERS, 1998, 39 (26) : 4587 - 4590

← 1 2 3 4 5 →