Solid-phase synthesis of hydrophobic peptides on 1,6-hexanediol diacrylate crosslinked polystyrene resin: Comparison with merrifield resin

被引：0
作者：
Arunan, C [1 ]
Pillai, VNR [1 ]
机构：
[1] Mahatma Gandhi Univ, Sch Chem Sci, Kottayam 686560, Kerala, India
来源：
PROTEIN AND PEPTIDE LETTERS | 1999年 / 6卷 / 06期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A novel polymer support based on 1,6-hexanediol diacrylate and polystyrene was developed. The resin showed better solvation in solvents used for peptide synthesis than Merrifield resin. The synthetic utility of the new support has been illustrated with the synthesis of some hydrophobic peptides which have high affinity for aggregation. The yield and purity of the peptides were high compared to when Merrifield resin was used.
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页码：391 / 398
页数：8
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