Do macrophages kill through apoptosis?

被引：63

作者：

Aliprantis, AO ^{[1
]}

DiezRoux, G ^{[1
]}

Mulder, LCF ^{[1
]}

Zychlinsky, A ^{[1
]}

Lang, RA ^{[1
]}

机构：

[1] NYU, MED CTR, SKIRBALL INST BIOMOL MED, DEPT PATHOL & MICROBIOL, NEW YORK, NY 10016 USA

来源：

IMMUNOLOGY TODAY | 1996年 / 17卷 / 12期

关键词：

D O I：

10.1016/S0167-5699(96)10071-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Macrophages can kill target cells independent of conventional immune specificity. Based on a re-examination of literature three decades old and recent experiments, Antonios Aliprantis and colleagues propose that macrophages kill target cells by inducing apoptosis. For this purpose, macrophages employ a selection of pro-apoptotic mediators including reactive oxygen and nitrogen species and tumour necrosis factor alpha.

引用

页码：573 / 576

页数：4

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