Effects of Hypericum calycinum L extract on the central nervous system in mice

被引:0
作者
Ozturk, Y [1 ]
Aydin, S [1 ]
Beis, R [1 ]
Baser, KHC [1 ]
Berberoglu, H [1 ]
机构
[1] STATE HOSP,DEPT BIOCHEM,ESKISEHIR,TURKEY
关键词
Hypericum calycinum; antidepressant drugs; depression; analgesia; central nervous system;
D O I
10.1002/(SICI)1099-1573(199612)10:8<700::AID-PTR929>3.0.CO;2-X
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Hypericum species have been used as herbal remedies for the therapy of various neurological disorders. In the present study, the effects of Hypericum calycinum on the central nervous system were investigated using various behavioural models including swimming time, locomotor activity, tail-flick and hole-board experiments. According to the results obtained, it was found that the extract prepared from H. calycinum is as effective as the antidepressant drugs, desipramine and trimipramine, which were used for comparison with this plant extract in animal models.
引用
收藏
页码:700 / 702
页数:3
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