Neuro-meningeal cryptococcal infection revealing a multiple myeloma

被引：6

作者：

Sayhi, Sameh ^{[1
]}

Bouzidi, Sawsen ^{[2
]}

Beji, Imen ^{[1
]}

Nasr, Aman Allah ^{[2
]}

Hannachi, Souha ^{[1
]}

Bedoui, Ines ^{[3
]}

Layouni, Samy ^{[2
,4
]}

Fekih-Mrissa, Najiba ^{[4
]}

Louzir, Bassem ^{[1
]}

Nsiri, Brahim ^{[2
]}

Abid, Rym ^{[1
]}

Battikh, Riadh ^{[1
]}

机构：

[1] Mil Hosp, Dept Internal Med, Tunis, Tunisia

[2] Mil Hosp, Lab Hematol, Tunis, Tunisia

[3] Mil Hosp, Dept Neurol, Tunis, Tunisia

[4] Mil Hosp, Mol Biol Unit, Lab Hematol, UR17DN06, Tunis, Tunisia

来源：

PAN AFRICAN MEDICAL JOURNAL | 2020年 / 36卷

关键词：

Cryptococcal-meningitis; multiple myeloma; hypogammaglobulinemia; lymphopenia; CELLS;

D O I：

10.11604/pamj.2020.36.324.20407

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Rare cases of Cryptococcus have been documented in patients living with multiple myeloma. To date there has been no documented evidence of cryptococcosis revealing multiple myeloma. We reported a 63-year-old man who had a 2-months history continuous holocranial headaches, morning vomiting, complaining of blurred vision and fever. The biologic and the imaging showed a Cryptococcus meningoencephalitis. The search for a cause of immunodeficiency revealed a multiple myeloma. The diagnosis for Cryptococcus was confirmed according to an India ink stain, blood and cerebrospinal fluid culture. The patient's treatment for multiple myeloma was initiated with a chemotherapy regimen. The evolution was good without complication. Cryptococcosis, especially in the neuro-meningeal form, is a serious, deadly opportunistic infection. The search of an underlining immunodeficiency must be systematic. In this case, it was associated with early stage multiple myeloma.

引用

页码：1 / 7

页数：7

共 15 条

[1]

Abassi Mahsa, 2015, Curr Trop Med Rep, V2, P90

[2] Cryptococcosis in late stage multiple myeloma: consider it [J].