Regio- and stereoselective hydrohalogenation of ynamide components in 1,3-butadiynes with in situ generated HX

被引：14

作者：

Ide, Masataka ^{[1
]}

Ohashi, Kazuhiro ^{[1
]}

Mihara, Shigenori ^{[1
]}

Iwasawa, Tetsuo ^{[1
]}

机构：

[1] Ryukoku Univ Otsu, Fac Sci & Technol, Dept Mat Chem, Shiga 5202194, Japan

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 13期

关键词：

Haloenamide; Diene; Hydrohalogenation; Regio- and stereoselective reaction; Enyne; COENZYME-A REDUCTASE; VINYL HALIDES; ALKYNES; ALKENES; ML-236B; I-2; IODOTRIMETHYLSILANE; STEREOCHEMISTRY; HYDROIODINATION; PATHWAYS;

D O I：

10.1016/j.tetlet.2014.02.028

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple protocol for regio-, and stereoselective hydrohalogenation of ynamide moieties in 1,3-butadiyne structures is described. The facile approach enables exact syn-addition of HX to the diyne components, giving just single isomer of the corresponding dienes and enynes. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：2130 / 2133

页数：4

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