Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: A brief review

被引：192

作者：

Khlyustova, Anna ^{[1
,2
]}

Labay, Cedric ^{[1
,2
]}

Machala, Zdenko ^{[3
]}

Ginebra, Maria-Pau ^{[1
,2
]}

Canal, Cristina ^{[1
,2
]}

机构：

[1] Univ Politecn Cataluna, Dept Mat Sci & Met, Biomat Biomech & Tissue Engn Grp, Barcelona 08019, Spain

[2] Univ Politecn Cataluna, Res Ctr Multiscale Sci & Engn, Barcelona 08019, Spain

[3] Comenius Univ, Fac Math Phys & Informat, Bratislava 84248, Slovakia

来源：

FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING | 2019年 / 13卷 / 02期

基金：

欧洲研究理事会;

关键词：

atmospheric plasma jets; liquids; ROS; RNS; plasma-dose; COLD ATMOSPHERIC PLASMA; HYDROGEN-PEROXIDE; NONTHERMAL PLASMA; DEGRADATION; DISCHARGE; WATER;

D O I：

10.1007/s11705-019-1801-8

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Reactive oxygen and nitrogen species (RONS) are among the key factors in plasma medicine. They are generated by atmospheric plasmas in biological fluids, living tissues and in a variety of liquids. This ability of plasmas to create a delicate mix of RONS in liquids has been used to design remote or indirect treatments for oncological therapy by treating biological fluids by plasmas and putting them in contact with the tumour. Documented effects include selective cancer cell toxicity, even though the exact mechanisms involved are still under investigation. However, the right dose for suitable therapeutical activity is crucial and still under debate. The wide variety of plasma sources hampers comparisons. This review focuses on atmospheric pressure plasma jets as the most studied plasma devices in plasma medicine and compiles the conditions employed to generate RONS in relevant liquids and the concentration ranges obtained. The concentrations of H2O2, NO2-, NO3- and short-lived oxygen species are compared critically to provide a useful overview for the reader.

引用

页码：238 / 252

页数：15

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