Gas-phase self-assembly of soft nanocomposites for efficient gene transfection and photothermal therapy

被引:5
作者
Byeon, Jeong Hoon [1 ]
Kim, Young-Woo [2 ]
机构
[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA
[2] Hoseo Univ, Dept Automot Engn, Asan 336795, South Korea
关键词
AEROSOL-BASED FABRICATION; IN-SITU SYNTHESIS; GOLD NANOPARTICLES; WATER-PURIFICATION; FILMS; GRAPHENE; NANOSTRUCTURES; FRAGMENTATION; IRRADIATION; GENERATION;
D O I
10.1039/c4tb00271g
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
The gene transfection efficiency of Au@PDMS-PLL soft nanocomposites was higher than those of SiO2-PLL and PEI; and moreover, the nanocomposites did not show significant cell cytotoxicity in in vitro measurements. The soft nanocomposites were also sensitive during photothermal therapy with infrared light, which produced a cytotoxic effect on the targeted HeLa cells.
引用
收藏
页码:3185 / 3189
页数:5
相关论文
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