Risks associated with vaccinia virus in the laboratory

被引：19
作者：
MacNeil, Adam [1 ]
Reynolds, Mary G. [1 ]
Damon, Inger K. [1 ]
机构：
[1] Ctr Dis Control & Prevent, Poxvirus & Rabies Branch, Div Viral & Rickettsial Dis, Natl Ctr Zoonot Vector Borne & Enter Dis, Atlanta, GA 30333 USA
来源：
VIROLOGY | 2009年 / 385卷 / 01期
关键词：
Vaccinia; Laboratory acquired infection; Orthopoxvirus; Vaccination; Smallpox vaccine; SMALLPOX VACCINATION; ACCIDENTAL INFECTION; HUMAN MONKEYPOX; WORKER; EXPRESSION; VECTOR;
D O I：
10.1016/j.virol.2008.11.045
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Vaccinia Virus (VACV) is used commonly in research laboratories. Non-highly attenuated strains of VACV are potentially pathogenic in humans, and VACV vaccination and biosafety level 2 facilities and protocols are currently recommended for vaccinated laboratory workers in the United States who handle non-highly attenuated strains of the virus. Despite this, laboratory-related VACV exposures continue to occur and a number of recent instances of VACV infection in non-vaccinated laboratory workers have been documented. We provide a discussion of the usage and risks associated with VACV in laboratory research. Published by Elsevier Inc.
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页码：1 / 4
页数：4
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