Comparative study of permanganate oxidation reactions of nucleotide bases by spectroscopy

被引:17
作者
Bui, CT [1 ]
Cotton, RGH [1 ]
机构
[1] Univ Melbourne, Genom Disorders Res Ctr, Melbourne, Vic 3065, Australia
关键词
KMnO4; oxidation reaction; nucleotide bases; spectroscopy;
D O I
10.1006/bioo.2002.1238
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The permanganate oxidation of free nucleotide bases was successfully studied in aqueous solution of tetraethylammonium chloride using spectroscopic techniques. The reaction was highly selective toward thymine and uracil, less with cytosine, very little reaction on guanine, and no reaction on adenine. (C) 2002 Elsevier Science (USA).
引用
收藏
页码:133 / 137
页数:5
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