Macroelectromyography: A review of the technique and its value in the investigation of neuromuscular disorders

The background for the macroelectromyography technique, which was developed by Erik Stalberg to measure the size of motor unit potentials in human muscles, is reviewed. The method employs a modified single-fiber electrode with a large nonselective recording surface capable of recording the activity from all the fibers of a motor unit. The findings in normal subjects and its application in the study of motor unit recruitment are described. The value of the technique in the investigation, diagnosis, and monitoring of various neuromuscular diseases, including primary myopathies and neurogenic conditions, is discussed. (C) 2002 Wiley Periodicals, Inc.