Asymmetric cyclopropanation of electron-rich alkenes by the racemic diene rhodium catalyst: the chiral poisoning approach

被引：5

作者：

Trifonova, Evgeniya A. ^{[1
]}

Ankudinov, Nikita M. ^{[1
]}

Chusov, Denis A. ^{[1
]}

Nelyubina, Yulia, V ^{[1
]}

Perekalin, Dmitry S. ^{[1
]}

机构：

[1] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, 28 Vavilova Str, Moscow 119991, Russia

来源：

CHEMICAL COMMUNICATIONS | 2022年 / 58卷 / 47期

基金：

俄罗斯科学基金会;

关键词：

INSERTION; NUCLEOPHILICITY; ACCESS; BOND;

D O I：

10.1039/d2cc01648f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric cyclopropanation of alkenes by aryldiazoacetates was achieved using the readily-available racemic (diene)rhodium complex in combination with the chiral oxazoline-phenol ligand, which acts as the chiral poison and selectively inhibits one of the enantiomers of the catalyst. This approach eliminates a common problematic step of the synthesis of chiral catalysts.

引用

页码：6709 / 6712

页数：4