Factors predicting prognosis with oncology patients followed in the intensive care unit

被引:1
作者
Ogul, Ali [1 ]
Paydas, Semra [2 ]
Karakoc, Emre [3 ]
Seydaoglu, Gulsah [4 ]
Buyuksimsek, Mahmut [1 ]
机构
[1] Adana City Educ & Res Hosp, Dept Med Oncol, Adana, Turkey
[2] Cukurova Univ, Dept Med Oncol, Fac Med, Adana, Turkey
[3] Cukurova Univ, Dept Intens Care Unit, Fac Med, Adana, Turkey
[4] Cukurova Univ, Dept Biostat, Fac Med, Adana, Turkey
来源
CUKUROVA MEDICAL JOURNAL | 2020年 / 45卷 / 04期
关键词
Intensive care unit; oncology patients; beta; 2; microglobulin; mortality; MELATONIN; MORTALITY; IMPACT; SLEEP;
D O I
10.17826/cumj.789199
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose: The aim of the study is to determine the factors affecting the mortality of oncology patients followed in the intensive care unit (ICU). Materials and Methods: In this study 100 patients who were followed up in the ICU of Cukurova University Faculty of Medicine, Internal Medicine Department between 2012-2014 were prospectively included. Acute Physiology and Chronic Health Evaluation (APACHE) II, 1st and 3rd day Sequential Organ Failure Assessment Score (SOFA) scores were used to determine the factors that were affecting mortality. Lactate, magnesium, phosphorus, potassium, blood urea nitrogen (BUN) and beta 2 microglobulin levels were determined at the time of admission to ICU. The relationship between vasopressor, renal, respiratory support need, neutropenia, infectious agents and mortality was determined during the follow-up period in the ICU. The patients were divided into two groups as patients transferred from ICU to the inpatient clinics (Group 1: 40 patients) and patients who were died in the ICU follow-up (Group 2: 60 patients). Results: APACHE II and 1st and 3rd day SOFA scores, predictive mortality rate, intensive care admission lactate levels, vasopressor and respiratory support needs, renal support needs, BUN, potassium and magnessium levels, beta 2 microglobulin levels, positive Acinetobacter baumannii culture mean was statistically significant with mortality during intensive care follow up between the Group 1 and 2 patients. In addition, mortality was found to be less in patients who were followed up in the new ICU. Conclusion: Beta 2 microglobulin level can be used to predict intensive care mortality.
引用
收藏
页码:1267 / 1275
页数:9
相关论文
共 22 条
[1]  
Al-Samsam Rim H, 2005, Pediatr Crit Care Med, V6, P562, DOI 10.1097/01.PCC.0000165561.40986.A6
[2]   PLASMA BETA-2 MICROGLOBULIN AS A MARKER OF FRAILTY IN OLDER ADULTS: A PILOT STUDY [J].
Annweiler, Cedric ;
Bataille, Regis ;
Ferriere, Nicolas ;
Douillet, Delphine ;
Fantino, Bruno ;
Beauchet, Olivier .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2011, 66 (10) :1077-1079
[3]   Blood Urea Nitrogen (BUN) is independently associated with mortality in critically ill patients admitted to ICU [J].
Arihan, Okan ;
Wernly, Bernhard ;
Lichtenauer, Michael ;
Franz, Marcus ;
Kabisch, Bjoern ;
Muessig, Johanna ;
Masyuk, Maryna ;
Lauten, Alexander ;
Schulze, Paul Christian ;
Hoppe, Uta C. ;
Kelm, Malte ;
Jung, Christian .
PLOS ONE, 2018, 13 (01)
[4]  
BATAILLE R, 1984, BLOOD, V63, P468
[5]   Severity scoring systems in the critically ill [J].
Bouch, D. Christopher ;
Thompson, Jonathan P. .
BJA EDUCATION, 2008, 8 (05) :181-185
[6]   Mechanisms of disease: Chronic lymphocytic leukemia [J].
Chiorazzi, N ;
Rai, KR ;
Ferrarini, M .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (08) :804-815
[7]   Outcome of older patients requiring ventilatory support in intensive care:: Impact of nutritional status [J].
Dardaine, V ;
Dequin, PF ;
Ripault, H ;
Constans, T ;
Giniès, G .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2001, 49 (05) :564-570
[8]  
Goodfellow PN, 1975, NATURE, P254
[9]  
Higgins TL., 2005, TXB CRITICAL CARE, P2195
[10]  
Holmes CL, 2005, ASSESSMENT SEVERITY, P63