Lead is a highly toxic metal that is pervasive in the environment in industrialised countries. There is universal agreement that at some level of exposure, lead damages the haematopoietic, renal, and neurological systems. However there is less agreement about how much lead can be tolerated without harm. The use of leaded petrol was phased out between 1976 and 1996 in the United States, and was eliminated in the European Union by 2000, but concern is growing that petrol remains an important source of exposure in many countries, especially in Africa and Asia. Motivated by this concern, the Seychelles Bureau of Standards implemented an air quality monitoring project to measure airborne lead in Victoria, the capital, beginning in January 1998. In this paper, we describe the potential dangers of human exposure to lead, focusing on the neurobehavioural effects in children. We describe some of the common and not so common sources of lead in the environment, emphasizing exposure from inhalation of airborne lead particles from automobile exhaust. The Seychelles Ambient Air Quality Monitoring Programme is described, including the collection and analytical methods used to measure the lead concentrations in these samples. We present the findings from this investigation and discuss their public health implications.
机构:
Tulane Sch Med, Dept Pharmacol, New Orleans, LA 70112 USATulane Sch Med, Dept Pharmacol, New Orleans, LA 70112 USA
Mielke, Howard W.
Gonzales, Christopher R.
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Tulane Sch Med, Dept Pharmacol, New Orleans, LA 70112 USA
Lead Lab Inc, New Orleans, LA 70119 USATulane Sch Med, Dept Pharmacol, New Orleans, LA 70112 USA
Gonzales, Christopher R.
Powell, Eric T.
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Lead Lab Inc, New Orleans, LA 70119 USATulane Sch Med, Dept Pharmacol, New Orleans, LA 70112 USA
Powell, Eric T.
Laidlaw, Mark A. S.
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机构:Tulane Sch Med, Dept Pharmacol, New Orleans, LA 70112 USA
Laidlaw, Mark A. S.
Berry, Kenneth J.
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机构:
Colorado State Univ, Dept Stat, Ft Collins, CO 80523 USATulane Sch Med, Dept Pharmacol, New Orleans, LA 70112 USA
Berry, Kenneth J.
Mielke, Paul W., Jr.
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Colorado State Univ, Dept Stat, Ft Collins, CO 80523 USATulane Sch Med, Dept Pharmacol, New Orleans, LA 70112 USA
Mielke, Paul W., Jr.
Egendorf, Sara Perl
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CUNY, Grad Ctr, Adv Sci Res Ctr, New York, NY 10031 USA
CUNY Brooklyn Coll, New York, NY 10031 USATulane Sch Med, Dept Pharmacol, New Orleans, LA 70112 USA
机构:
Shahid Beheshti Univ Med Sci, Fac Paramed Sci, Dept Biostat, Tehran, IranShahid Beheshti Univ Med Sci, Fac Paramed Sci, Dept Biostat, Tehran, Iran
Heidari, Serve
Mostafaei, Shayan
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Kermanshah Univ Med Sci, Fac Hlth, Dept Biostat, Kermanshah, Iran
Univ Tehran Med Sci, Rheumatol Res Ctr, Epidemiol Biostat Unit, Tehran, IranShahid Beheshti Univ Med Sci, Fac Paramed Sci, Dept Biostat, Tehran, Iran
Mostafaei, Shayan
Razazian, Nazanin
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Kermanshah Univ Med Sci, Sch Med, Dept Neurol, Imam Reza Hosp, Kermanshah, IranShahid Beheshti Univ Med Sci, Fac Paramed Sci, Dept Biostat, Tehran, Iran
Razazian, Nazanin
Rajati, Mojgan
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机构:
Kermanshah Univ Med Sci, Sch Med, Dept Obstet & Gynecol, Motazedi Hosp,Obstet & Gynecol, Kermanshah, IranShahid Beheshti Univ Med Sci, Fac Paramed Sci, Dept Biostat, Tehran, Iran
Rajati, Mojgan
Saeedi, Anahita
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Univ Massachusetts, Dept Biostat, Sch Publ Hlth & Hlth Sci, Amherst, MA 01003 USAShahid Beheshti Univ Med Sci, Fac Paramed Sci, Dept Biostat, Tehran, Iran
Saeedi, Anahita
Rajati, Fatemeh
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Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Hlth Inst, Kermanshah, IranShahid Beheshti Univ Med Sci, Fac Paramed Sci, Dept Biostat, Tehran, Iran
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Univ Fed Bahia, Fac Pharm, Immunol Serv Infect Dis, Salvador, BA, Brazil
Univ Fed Bahia, Fac Pharm, Grad Program Pharm, Salvador, BA, BrazilUniv Fed Bahia, Fac Pharm, Immunol Serv Infect Dis, Salvador, BA, Brazil
Martinez, Victor O.
de Mendonca Lima, Fernanda W.
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Univ Fed Bahia, Fac Pharm, Immunol Serv Infect Dis, Salvador, BA, BrazilUniv Fed Bahia, Fac Pharm, Immunol Serv Infect Dis, Salvador, BA, Brazil
de Mendonca Lima, Fernanda W.
Alecrim Rocha, Romula B.
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Univ Fed Bahia, Fac Pharm, Grad Program Pharm, Salvador, BA, BrazilUniv Fed Bahia, Fac Pharm, Immunol Serv Infect Dis, Salvador, BA, Brazil
Alecrim Rocha, Romula B.
Ferreol Bah, Homegnon A.
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Univ Fed Bahia, Fac Pharm, Grad Program Pharm, Salvador, BA, BrazilUniv Fed Bahia, Fac Pharm, Immunol Serv Infect Dis, Salvador, BA, Brazil
Ferreol Bah, Homegnon A.
Carvalho, Chrissie F.
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Univ Fed Santa Catarina, Dept Psychol, Florianopolis, SC, BrazilUniv Fed Bahia, Fac Pharm, Immunol Serv Infect Dis, Salvador, BA, Brazil
Carvalho, Chrissie F.
Menezes-Filho, Jose Antonio
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Univ Fed Bahia, Fac Pharm, Lab Toxicol, Salvador, BA, Brazil
Univ Fed Bahia, Fac Pharm, Grad Program Pharm, Salvador, BA, BrazilUniv Fed Bahia, Fac Pharm, Immunol Serv Infect Dis, Salvador, BA, Brazil
机构:
Univ Paris Est, ESE Sante, CSTB, F-77447 Champs Sur Marne 2, Marne La Vallee, France
Univ Nantes, EA Biostat Rech Clin & Mesures Subject Sante 4275, F-44035 Nantes 1, FranceUniv Paris Est, ESE Sante, CSTB, F-77447 Champs Sur Marne 2, Marne La Vallee, France
Lucas, Jean-Paul
Le Bot, Barbara
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机构:
EHESP, F-35043 Rennes, France
INSERM, U1085, IRSET, F-35043 Rennes, FranceUniv Paris Est, ESE Sante, CSTB, F-77447 Champs Sur Marne 2, Marne La Vallee, France
Le Bot, Barbara
Glorennec, Philippe
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机构:
EHESP, F-35043 Rennes, France
INSERM, U1085, IRSET, F-35043 Rennes, FranceUniv Paris Est, ESE Sante, CSTB, F-77447 Champs Sur Marne 2, Marne La Vallee, France
Glorennec, Philippe
Etchevers, Anne
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INSERM, U1085, IRSET, F-35043 Rennes, France
InVS, F-94415 St Maurice, FranceUniv Paris Est, ESE Sante, CSTB, F-77447 Champs Sur Marne 2, Marne La Vallee, France
Etchevers, Anne
Bretin, Philippe
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InVS, F-94415 St Maurice, FranceUniv Paris Est, ESE Sante, CSTB, F-77447 Champs Sur Marne 2, Marne La Vallee, France
Bretin, Philippe
Douay, Francis
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机构:
Univ Lille Nord France, Lille, France
Grp ISA, Equipe Sols & Environm, LGCgE, Lille Nord France EA 4515, F-59046 Lille, FranceUniv Paris Est, ESE Sante, CSTB, F-77447 Champs Sur Marne 2, Marne La Vallee, France
Douay, Francis
Sebille, Veronique
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机构:
Univ Nantes, EA Biostat Rech Clin & Mesures Subject Sante 4275, F-44035 Nantes 1, FranceUniv Paris Est, ESE Sante, CSTB, F-77447 Champs Sur Marne 2, Marne La Vallee, France
Sebille, Veronique
Bellanger, Lise
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机构:
CNRS, UMR 6629, Lab Math Jean Leray, F-44322 Nantes, FranceUniv Paris Est, ESE Sante, CSTB, F-77447 Champs Sur Marne 2, Marne La Vallee, France
Bellanger, Lise
Mandin, Corinne
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Univ Paris Est, ESE Sante, CSTB, F-77447 Champs Sur Marne 2, Marne La Vallee, FranceUniv Paris Est, ESE Sante, CSTB, F-77447 Champs Sur Marne 2, Marne La Vallee, France