Two New Anxiolytic Phenanthrenes Found in the Medullae of Juncus effusus

被引：1

作者：

Wang, Yang ^{[1
]}

Li, Gui-Yun ^{[1
]}

Fu, Qian ^{[1
]}

Hao, Tai-Sen ^{[1
]}

Huang, Jian-Mei ^{[1
]}

Zhai, Hai-Feng ^{[2
]}

机构：

[1] Beijing Univ Chinese Med, Sch Chinese Mat Med, Beijing 100102, Peoples R China

[2] Peking Univ, Natl Inst Drug Dependence, Beijing 100191, Peoples R China

来源：

NATURAL PRODUCT COMMUNICATIONS | 2014年 / 9卷 / 08期

基金：

中国国家自然科学基金;

关键词：

Juncus effusus; Phenanthrene; Anxiolytic;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Six phenanthrenes, 2-methoxy-7-hydroxy-1-methyl-5-vinyl phenanthrene (1), juncusin (2), dehydroeffusol (3), juncusol (4), effusol (5), and dehydroeffusal (6), were isolated from the medullae of Juncus effusus L. Compounds 1 and 2 were identified as being new structures, and both of them showed anxiolytic activity at dosages of 10 and 2.5 mg/kg, respectively.

引用

页码：1177 / 1178

页数：2