Ortho C-H Acylation of Aryl Iodides by Palladium/Norbornene Catalysis

被引：160
作者：
Dong, Zhe [1 ]
Wang, Jianchun [1 ]
Ren, Zhi [1 ]
Dong, Guangbin [1 ]
机构：
[1] Univ Texas Austin, Dept Chem, Austin, TX 78712 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 43期
关键词：
acylation; arenes; C-H activation; heterocycles; palladium; CROSS-COUPLING REACTIONS; CARBOXYLIC ANHYDRIDES; PALLADIUM; KETONES; NORBORNENE; ACTIVATION; ARYLATION; SEQUENCE; INDOLES; CASCADE;
D O I：
10.1002/anie.201506397
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Reported herein is a palladium/norbornene-catalyzed ortho-arene acylation of aryl iodides by a Catellani-type C-H functionalization. This transformation is enabled by isopropyl carbonate anhydrides, which serve as both an acyl cation equivalent and a hydride source.
引用
收藏
页码：12664 / 12668
页数：5
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