Evidence of effectiveness from a large county-wide school-based influenza immunization campaign

被引：14

作者：

Grijalva, Carlos G. ^{[1
]}

Zhu, Yuwei ^{[2
]}

Griffin, Marie R. ^{[1
,3
]}

机构：

[1] Vanderbilt Univ, Sch Med, Dept Prevent Med, Nashville, TN 37232 USA

[2] Vanderbilt Univ, Sch Med, Dept Biostat, Nashville, TN 37232 USA

[3] Vanderbilt Univ, Sch Med, Dept Med, Nashville, TN 37232 USA

来源：

VACCINE | 2009年 / 27卷 / 20期

关键词：

Live attenuated influenza vaccine; School-based immunization; Influenza; Rapid influenza tests; VACCINE; CHILDREN; TRIVALENT; IMMUNITY; BURDEN; ADULTS; IMPACT;

D O I：

10.1016/j.vaccine.2009.02.039

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A school-based campaign in Knox County, TN immunized 41% and 48% of school children with live attenuated influenza vaccine in 2005 and 2006, respectively. We computed the relative risk (RR) of a positive rapid influenza testing Knox compared to Knox-surrounding county children (controls)during live baseline and two campaign seasons. Among children aged <5 years, the RR for a positive test remained relatively constant throughout the study seasons. Among children aged 5-17 years (target population), the RR was I during baseline and declined by 21% (RR, 0.79; 95% CI, 0.59-1.05) and 27% (RR, 0.73; 95% CI, 0.60-0.87) during the first and second campaign season, respectively. These findings suggest a direct beneficial effect of the immunization campaign. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：2633 / 2636

页数：4

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