A one-pot synthesis of 3-arylglutaric anhydrides by reaction of ketene with aromatic aldehydes and ketones

被引：5

作者：

Matsunaga, Hirokazu ^{[1
]}

Ikeda, Kiyoshi ^{[1
]}

Iwamoto, Ken-ichi ^{[1
]}

Suzuki, Yumiko ^{[1
]}

Sato, Masayuki ^{[1
]}

机构：

[1] Univ Shizuoka, Sch Pharmaceut Sci, Suruga Ku, Shizuoka 4228526, Japan

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 20期

关键词：

DESYMMETRIZATION;

D O I：

10.1016/j.tetlet.2009.02.193

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aromatic aldehydes and ketones react with ketene under Lewis acid catalysis to produce beta-lactones, which in situ react with another molecule of ketene to produce 3-arylglutaric anhydrides. The mechanism, scope, and limitation of this one-pot synthesis of 3-substituted glutaric anhydrides are discussed. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：2334 / 2336

页数：3