MR Spectroscopic Evidence of Brain Injury in the Non-Diagnosed Collision Sport Athlete

被引:75
作者
Poole, Victoria N. [1 ,2 ]
Abbas, Kausar [3 ]
Shenk, Trey E. [3 ]
Breedlove, Evan L. [4 ,5 ]
Breedlove, Katherine M.
Robinson, Meghan E. [1 ]
Leverenz, Larry J. [5 ]
Nauman, Eric A. [1 ,2 ,4 ]
Talavage, Thomas M. [1 ,3 ]
Dydak, Ulrike [6 ,7 ]
机构
[1] Purdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47907 USA
[2] Purdue Univ, Dept Basic Med Sci, W Lafayette, IN 47907 USA
[3] Purdue Univ, Sch Elect & Comp Engn, W Lafayette, IN 47907 USA
[4] Purdue Univ, Sch Mech Engn, W Lafayette, IN 47907 USA
[5] Purdue Univ, Dept Hlth & Kinesiol, W Lafayette, IN 47907 USA
[6] Purdue Univ, Sch Hlth Sci, W Lafayette, IN 47907 USA
[7] Indiana Univ Sch Med, Dept Radiol & Imaging Sci, Indianapolis, IN 46202 USA
关键词
MAGNETIC-RESONANCE-SPECTROSCOPY; CHRONIC TRAUMATIC ENCEPHALOPATHY; HIGH-SCHOOL FOOTBALL; METABOLIC-CHANGES; IN-VIVO; CHOLINE METABOLITES; HEAD-INJURY; CONCUSSION; GLUTAMINE; CHILDREN;
D O I
10.1080/87565641.2014.940619
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
With growing evidence of long-term neurological damage in individuals enduring repetitive head trauma, it is critical to detect lower-level damage accumulation for the early diagnosis of injury in at-risk populations. Proton magnetic resonance spectroscopic scans of the dorsolateral prefrontal cortex and primary motor cortex were collected from high school American (gridiron) football athletes, prior to and during their competition seasons. Although no concussions were diagnosed, significant metabolic deviations from baseline and non-collision sport controls were revealed. Overall the findings indicate underlying biochemical changes, consequential to repetitive hits, which have previously gone unnoticed due to a lack of traditional neurological symptoms.
引用
收藏
页码:459 / 473
页数:15
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