Does epidural versus combined spinal-epidural analgesia prolong labor and increase the risk of instrumental and cesarean delivery in nulliparous women?

被引:14
作者
Aneiros, Francisco [1 ,2 ]
Vazquez, Miriam [1 ,2 ]
Valino, Cristina [1 ,2 ]
Taboada, Manuel [1 ,2 ]
Sabate, Sergi [3 ]
Otero, Pablo [1 ,2 ]
Costa, Jose [1 ,2 ]
Carceller, Javier [1 ,2 ]
Vazquez, Rocio [1 ,2 ]
Diaz-Vieito, Maria [1 ,2 ]
Rodriguez, Alfonso [1 ,2 ]
Alvarez, Julian [1 ,2 ]
机构
[1] Univ Santiago de Compostela, Dept Anesthesiol, Santiago De Compostela 15706, Spain
[2] Hosp Clin Univ Santiago, Santiago De Compostela 15706, Spain
[3] Fdn Puigvert INUA, Dept Anesthesiol, Barcelona 08025, Spain
关键词
Analgesia; Obstetrical; Analgesic techniques; Combined spinal-epidural; Epidural; Subarachnoid; BUPIVACAINE; LEVOBUPIVACAINE; ROPIVACAINE; SUFENTANIL; INFUSION;
D O I
10.1016/j.jclinane.2008.06.020
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Study Objective: To compare duration of labor, mode of delivery, and local anesthetic consumed in women who received labor analgesia with epidural or combined spinal-epidural technique. Design: Retrospective, observational study. Setting: Delivery room of a university hospital. patients: 788 nulliparous women in labor at term with cervical dilation between three and 5 cm. Interventions: In Group E (epidural alone), parturients received an epidural solution of 8 mL (levobupivacaine 0.125% with fentanyl 5 mu g/mL). In Group CSE (combined spinal-epidural), parturients received a spinal injection of levobupivacaine two mg with fentanyl 15 mu g (total volume two mL). Then an epidural catheter was placed in all patients and connected to a patient-controlled analgesia pump (basal infusion rate of 8 mL/hr of 0.1% levobupivacaine and fentanyl two mu g/mL, patient-controlled bolus dose of three mL, and lockout time of 30 min). Measurements: Labor duration, mode of delivery (spontaneous vaginal vs. instrumental delivery vs. cesarean section), and local anesthetic consumed, were recorded. Main Results: Labor analgesia was performed with an epidural technique in 322 patients (40.9%), and a combined spinal-epidural technique in 466 patients (59.1%), of whom 39 Group E women (12.1%) and 46 Group CSE women (9.9%) required cesarean section (P=ns). No differences in the mode of delivery were observed between the groups. Time from analgesia to delivery (Group E: 217 +/- 111 min vs. Group CSE: 213 +/- 115 min; P=ns), and epidural local anesthetic consumed (Group E: 35 +/- 20 mL vs. Group CSE: 33 20 mL; P=ns), were similar in both groups. Conclusions: No significant differences were observed between epidural and combined spinal-epidural given for labor analgesia in nulliparous women in duration of labor, mode of delivery, or local anesthetic consumed. (c) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:94 / 97
页数:4
相关论文
共 15 条
[1]   Minimum local analgesic doses of ropivacaine, levobupivacaine, and bupivacaine for intrathecal labor analgesia [J].
Camorcia, M ;
Capogna, G ;
Columb, MO .
ANESTHESIOLOGY, 2005, 102 (03) :646-650
[2]  
CAYACON N, 2006, J INT MED RES, V34, P596
[3]   RANDOMIZED COMPARISON OF COMBINED SPINAL-EPIDURAL AND STANDARD EPIDURAL ANALGESIA IN LABOR [J].
COLLIS, RE ;
DAVIES, DWL ;
AVELING, W .
LANCET, 1995, 345 (8962) :1413-1416
[4]   Comparison of low-dose epidural with combined spinal-epidural analgesia for labour [J].
Dresner, M ;
Bamber, J ;
Calow, C ;
Freeman, J ;
Charlton, P .
BRITISH JOURNAL OF ANAESTHESIA, 1999, 83 (05) :756-760
[5]   Comparison of combined spinal-epidural and low dose epidural for labour analgesia [J].
Hepner, DL ;
Gaiser, RR ;
Cheek, TG ;
Gutsche, BB .
CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2000, 47 (03) :232-236
[6]  
MacArthur C, 2001, LANCET, V358, P19
[7]   Patient-controlled epidural analgesia following combined spinal-epidural analgesia in labour: the effects of adding a continuous epidural infusion [J].
Missant, C ;
Teunkens, A ;
Vandermeersch, E ;
Van de Velde, M .
ANAESTHESIA AND INTENSIVE CARE, 2005, 33 (04) :452-456
[8]   Epidural analgesia compared with combined spinal-epidural analgesia during labor in nulliparous women [J].
Nageotte, MP ;
Larson, D ;
Rumney, PJ ;
Sidhu, M ;
Hollenbach, K .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (24) :1715-1719
[9]   Combined spinal-epidural versus epidural labor analgesia [J].
Norris, MC ;
Fogel, ST ;
Conway-Long, C .
ANESTHESIOLOGY, 2001, 95 (04) :913-920
[10]   Regional analgesia in early active labour: combined spinal epidural vs. epidural [J].
Price, C ;
Lafreniere, L ;
Brosnan, C ;
Findley, I .
ANAESTHESIA, 1998, 53 (10) :951-955