Array sensing using optical methods for detection of chemical and biological hazards

被引:290
作者
Diehl, Katharine L. [1 ]
Anslyn, Eric V. [1 ]
机构
[1] Univ Texas Austin, Dept Chem & Biochem, Austin, TX 78712 USA
关键词
COLORIMETRIC SENSOR ARRAY; PATTERN-RECOGNITION; FLUORESCENCE DETECTION; NOBEL LECTURE; IDENTIFICATION; EXPLOSIVES; ANALYTES; DISCRIMINATION; CLASSIFICATION; BACTERIA;
D O I
10.1039/c3cs60136f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
By mimicking the mammalian senses of taste and smell, artificial arrays of cross-reactive receptors have found use in a variety of sensing applications. Pattern recognition algorithms allow these arrays to be used for discriminating analytes and even for predicting the identity of unknown analytes. Furthermore, in selecting a signaling method for these assays, the choice of optical detection is particularly desirable due to its high sensitivity and the associated convenient instrumentation. This tutorial review provides a brief introduction to array sensing using optical detection and chemometrics. While differential sensing approaches have been used for a number of applications, this review focuses on progress towards the detection of chemical and biological hazards.
引用
收藏
页码:8596 / 8611
页数:16
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