Severity evaluation of obstructive sleep apnea based on speech features

被引:12
作者
Ding, Yiming [1 ,2 ,3 ]
Wang, Jiaxi [4 ]
Gao, Jiandong [4 ,5 ]
Fang, Qiang [6 ]
Li, Yanru [1 ,2 ,3 ]
Xu, Wen [1 ,2 ,3 ]
Wu, Ji [4 ,5 ]
Han, Demin [1 ,2 ,3 ]
机构
[1] Capital Med Univ, Beijing Tongren Hosp, 1 Dongjiaominxiang St, Beijing 100730, Peoples R China
[2] Capital Med Univ, Obstruct Sleep Apnea Hypopnea Syndrome Clin Diag, Beijing 100730, Peoples R China
[3] Capital Med Univ, Key Lab Otolaryngol Head & Neck Surg, Minist Educ, Beijing 100730, Peoples R China
[4] Tsinghua Univ, Dept Elect Engn, Room 8301,Luomu Bldg, Beijing, Peoples R China
[5] Tsinghua Univ, Ctr Big Data & Clin Res, Inst Precis Med, Room 8301,Luomu Bldg, Beijing, Peoples R China
[6] Chinese Acad Social Sci, Inst Linguist, Beijing, Peoples R China
关键词
Obstructive sleep apnea (OSA); Speech signal processing; Machine learning;
D O I
10.1007/s11325-020-02168-0
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Purpose There are upper airway abnormalities in patients with obstructive sleep apnea (OSA), and their speech signal characteristics are different from those of unaffected people. In this study, the severity of OSA was evaluated automatically by machine learning technology based on the speech signals of Chinese people. Methods In total, 151 adult male Mandarin native speakers who had suspected OSA completed polysomnography to assess the severity of the disease. Chinese vowels and nasal sounds were recorded in sitting and supine positions, and the accuracy of predicting the apnea-hypopnea index (AHI) of the participants using a machine learning method was analyzed based on features extracted from the speech signals. Results Among the 151 participants, 75 had AHI > 30 events/h, and 76 had AHI <= 30 events/h. Various features including linear prediction cepstral coefficients (LPCC) were extracted from the data collected from participants recorded in the sitting and supine positions and by using a linear support vector machine (SVM); we classified the participants with thresholds of AHI = 30 and AHI = 10 events/h. The accuracies of the classifications were both 78.8%, the sensitivities were 77.3% and 79.1%, and the specificities were 80.3% and 78.0%, respectively. Conclusion This study constructed a severity evaluation model of OSA based on speech signal processing and machine learning, which can be used as an effective method to screen patients with OSA. In addition, it was found that Chinese pronunciation can be used as an effective feature to predict OSA.
引用
收藏
页码:787 / 795
页数:9
相关论文
共 20 条
[1]   Speaker age estimation using i-vectors [J].
Bahari, Mohamad Hasan ;
McLaren, Mitchell ;
Hugo Van Hamme ;
van Leeuwen, David A. .
ENGINEERING APPLICATIONS OF ARTIFICIAL INTELLIGENCE, 2014, 34 :99-108
[2]   Rules for Scoring Respiratory Events in Sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events [J].
Berry, Richard B. ;
Budhiraja, Rohit ;
Gottlieb, Daniel J. ;
Gozal, David ;
Iber, Conrad ;
Kapur, Vishesh K. ;
Marcus, Carole L. ;
Mehra, Reena ;
Parthasarathy, Sairam ;
Quan, Stuart F. ;
Redline, Susan ;
Strohl, Kingman P. ;
Ward, Sally L. Davidson ;
Tangredi, Michelle M. .
JOURNAL OF CLINICAL SLEEP MEDICINE, 2012, 8 (05) :597-619
[3]   STOP-Bang Questionnaire A Practical Approach to Screen for Obstructive Sleep Apnea [J].
Chung, Frances ;
Abdullah, Hairil R. ;
Liao, Pu .
CHEST, 2016, 149 (03) :631-638
[4]   Reviewing the connection between speech and obstructive sleep apnea [J].
Espinoza-Cuadros, Fernando ;
Fernandez-Pozo, Ruben ;
Toledano, Doroteo T. ;
Alcazar-Ramirez, Jose D. ;
Lopez-Gonzalo, Eduardo ;
Hernandez-Gomez, Luis A. .
BIOMEDICAL ENGINEERING ONLINE, 2016, 15
[5]   Frontal and lateral cephalometry in patients with sleep-disordered breathing [J].
Finkelstein, Y ;
Wexler, D ;
Horowitz, E ;
Berger, G ;
Nachmani, A ;
Shapiro-Feinberg, M ;
Ophir, D .
LARYNGOSCOPE, 2001, 111 (04) :634-641
[6]   SPEECH DYSFUNCTION OF OBSTRUCTIVE SLEEP-APNEA - A DISCRIMINANT-ANALYSIS OF ITS DESCRIPTORS [J].
FOX, AW ;
MONOSON, PK ;
MORGAN, CD .
CHEST, 1989, 96 (03) :589-595
[7]   Obstructive sleep apnea is a common disorder in the population - a review on the epidemiology of sleep apnea [J].
Franklin, Karl A. ;
Lindberg, Eva .
JOURNAL OF THORACIC DISEASE, 2015, 7 (08) :1311-1322
[8]   Reduction in motor vehicle collisions following treatment of sleep apnoea with nasal CPAP [J].
George, CFP .
THORAX, 2001, 56 (07) :508-512
[9]  
Kriboy M, 2013, P ANN C AF AVIOS SPE, P1
[10]  
Lee BL, 2013, ELIFE, V2, DOI [10.7554/eLife.00291, 10.1155/2013/961957]