Vitamin E serum levels and gastric cancer: results from a cohort of patients in Tuscany, Italy

被引：11

作者：

Battisti, C

Formichi, P

Tripodi, SA

Vindigni, C

Roviello, F

Federico, A

机构：

[1] Univ Siena, Inst Neurol Sci, OU Neurometab Dis, I-53100 Siena, Italy

[2] Univ Siena, Inst Pathol, I-53100 Siena, Italy

[3] Univ Siena, Dept Surg, I-53100 Siena, Italy

来源：

CANCER LETTERS | 2000年 / 151卷 / 01期

关键词：

vitamin E; gastric cancer; histotype;

D O I：

10.1016/S0304-3835(99)00392-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Alpha-tocopherol has been reported to play an important role against oxidative damage and in the inhibition of cell transforming and mutagenesis. We analysed vitamin E serum levels in 51 cases of patients affected by gastric cancer at different stages of the disease, and in 49 age-matched controls. All patients had normal values of alpha-tocopherol. However, when patients have been grouped according to histotype of gastric lesions, a significant vitamin E increase has been found in diffuse gastric cancer histotype compared to the intestinal histotype. Our results suggest that a correlation between vitamin E serum levels and gastric cancer histotype should be considered. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：15 / 18

页数：4

共 25 条

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[12] VITAMIN-E REMAINS THE MAJOR LIPID-SOLUBLE, CHAIN-BREAKING ANTIOXIDANT IN HUMAN-PLASMA EVEN IN INDIVIDUALS SUFFERING SEVERE VITAMIN-E-DEFICIENCY [J].