An overview of osteoporosis and frailty in the elderly

被引：165
作者：
Li, Guowei [1 ,2 ,3 ]
Thabane, Lehana [1 ,2 ]
Papaioannou, Alexandra [4 ]
Ioannidis, George [4 ]
Levine, Mitchell A. H. [1 ,2 ,3 ]
Adachi, Jonathan D. [2 ,4 ,5 ]
机构：
[1] McMaster Univ, Dept Clin Epidemiol & Biostat, 1280 Main St West, Hamilton, ON L8S 4L8, Canada
[2] McMaster Univ, St Josephs Healthcare Hamilton, 25 Charlton Ave East, Hamilton, ON L8N 1Y2, Canada
[3] Ctr Evaluat Medicines, Programs Assessment Technol Hlth, Hamilton, ON L8N 1Y3, Canada
[4] McMaster Univ, Dept Med, 1280 Main St West, Hamilton, ON L8S 4L8, Canada
[5] McMaster Univ, St Josephs Healthcare Hamilton, 25 Charlton Ave East, Hamilton, ON L8N 1Y2, Canada
来源：
BMC MUSCULOSKELETAL DISORDERS | 2017年 / 18卷
关键词：
Osteoporosis; Osteoporotic fractures; Frailty; Geriatrics; Ageing; OLDER WOMEN; FRACTURE RISK; HIP FRACTURE; PHENOTYPE; MORTALITY; PEOPLE; DISABILITY; FALLS; INDEX; INSTRUMENTS;
D O I：
10.1186/s12891-017-1403-x
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Osteoporosis and osteoporotic fractures remain significant public health challenges worldwide. Recently the concept of frailty in relation to osteoporosis in the elderly has been increasingly accepted, with emerging studies measuring frailty as a predictor of osteoporotic fractures. In this overview, we reviewed the relationship between frailty and osteoporosis, described the approaches to measuring the grades of frailty, and presented current studies and future research directions investigating osteoporosis and frailty in the elderly. It is concluded that measuring the grades of frailty in the elderly could assist in the assessment, management and decision-making for osteoporosis and osteoporotic fractures at a clinical research level and at a health care policy level.
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页数：5
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